Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition


Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

Veterinary Toxicology, Basic And Clinical Principles, 3Rd Edition

Veterinary Toxicology, Basic and Clinical Principles, Third Edition, is a unique, single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level. While comparable texts are primarily directed on the field of human toxicology, this text thoroughly prepares toxicologists and students on the newest approaches for diagnosing chemical and plant poisoning cases in animals. Many chapters on topics not covered in any previous books are provided, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology.

Completely revised and updated to include the most recent developments in the field, including new toxins, methods and regions, this book is an essential resource for advanced students and researchers in toxicology, practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists and animal scientists.

  • Provides a complete, up-to-date, integrated source of information on toxins and poisons relating to animals
  • Covers all important aspects of veterinary toxicology with completely updated and revised chapters
  • Includes basic principles of a key toxicology concept, along with clinical applications and a list of major references for further reading
About The Author

Ramesh C. Gupta

Dr. Ramesh C. Gupta, Professor & Head of Toxicology Department at Murray State university, is engaged in research on pesticide toxicity, neurodegenerative diseases, and nutraceuticals efficacy and safety. He has delivered lectures in UK, Australia, Italy, Japan, Germany, France, Switzerland, Spain, Czech Republic, China, South Korea, Sweden, and Turkey. He served the panels of NIH, CDC, NIOSH, and NAS. He has >450 publications to his credit, including seven major books: (1) Toxicology of Organophosphate and Carbamate Compounds, (2) Veterinary Toxicology: Basic and Clinical Principles, (3) Handbook of Toxicology of Chemical Warfare Agents, (4) Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology, (5) Reproductive and Developmental Toxicology, (6) Biomarkers in Toxicology, (7) Nutraceuticals: Efficacy, Safety and Toxicity, and (8) Nutraceuticals in Veterinary Medicine. He is recipient of Murray State University’s distinguished researcher award of the year-2006, and Outstanding research award of the year 2014. In 2019, he received a medal from The Royal Academy of Spanish Veterinary Sciences for his distinguished services to veterinary medicine. He is a diplomate of American Board of Toxicology, and fellow of American College of Toxicology, American College of Nutrition, and Academy of Toxicological Sciences. Dr. Gupta is a member of many professional societies, including SOT, Eurotox, ASPET, American College of Toxicology, and ISSX.

Table of Contents

Section I: General
1. Concepts in veterinary toxicology
2. Toxicokinetics
3. Factors affecting chemical toxicity
4. Toxicological testing: in vivo and in vitro models
5. Epidemiology of animal poisonings in the United States
6. Epidemiology of animal poisonings in Europe
7. Epidemiology of animal poisonings in Asia
8. Chemicals of terrorism
9. Regulatory considerations in veterinary toxicology
10. Regulatory aspects for the drugs and chemicals used in food-producing animals in the European Union
11. Regulatory aspects for the drugs and chemicals used in Japan
12. Statistics in veterinary toxicology
13. Computational modeling in veterinary toxicology (New chapter)
14. Toxicology and the law

Section II: Organ Toxicity
15. Nervous system toxicity
16. Respiratory toxicity
17. Cardiovascular toxicity
18. Liver toxicity
19. Renal toxicity
20. Reproductive toxicity and endocrine disruption
21. Placental toxicity
22. Dermal toxicity
23. Blood and bone marrow toxicity
24. Immunotoxicity

Section III: Nanoparticles, Radiation and Carcinogens
25. Toxicity of nanomaterials
26. Ionizing radiation and radioactive materials in health and disease
27. Carcinogenesis: mechanisms and models

Section IV: Drugs of Use and Abuse
28. Toxicity of over-the-counter drugs
29. Toxicity of drugs of abuse

Section V: Metals and Micronutrients
30. Aluminum
31. Arsenic
32. Cadmium
33. Chromium, iodine and phosphorus
34. Copper
35. Fluoride
36. Iron
37. Lead
38. Manganese
39. Mercury
40. Molybdenum
41. Selenium
42. Sodium chloride (salt)
43. Sulfur
44. Zinc

Section VI: Insecticides and Molluscicides
45. Organophosphates and carbamates
46. Organochlorines
47. Pyrethrins and pyrethroids
48. Neonicotinoids
49. Amitraz
50. Fipronil
51. Macrocyclic lactone endectocides
52. Rotenone
53. Metaldehyde

Section VII: Herbicides and Fungicides
54. Toxicity of herbicides
55. Toxicity of fungicides

Section VIII: Rodenticides and Avicides
56. Anticoagulant rodenticides
57. Non-anticoagulant rodenticides
58. Avitrol

Section IX: Gases, Solvents and Other Industrial Toxicants
59. Toxic gases
60. Alcohols and glycols
61. Petroleum
62. Polychlorinated biphenyls, polybrominated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans
63. Polycyclic aromatic hydrocarbons
64. Brominated flame retardants and perfluorinated chemicals

Section X: Environmental Toxicology
65. Principles of ecotoxicology
66. Avian toxicology
67. Aquatic toxicology
68. Toxicology and diversity of marine toxins

Section XI: Bacterial and Cyanobacterial Toxins
69. Botulinum neurotoxins
70. Enterotoxins
71. Cyanobacterial (blue-green algae) toxins

Section XII: Poisonous and Venomous Organisms
72. Terrestrial zootoxins
73. Mare reproductive loss syndrome

Section XIII: Estrogenic Toxicants
74. Chemical-induced estrogenicity
75. Phytoestrogens

Section XIV: Poisonous Plants
76. Poisonous plants of the USA
77. Poisonous plants of Europe
78. Poisonous plants of Australia and New Zealand
79. Cyanogenic plants
80. Nitrate and nitrite accumulating plants
81. Toxicity of yew (Taxus spp.) alkaloids
82. Oxalate-containing plants
83. Mushroom toxins
84. Datura species and related plants
85. Cottonseed toxicity
86. Fescue toxicosis

Section XV: Mycotoxins
87. Aflatoxins
88. Ergot
89. Fumonisins
90. Ochratoxins and citrinin
91. Slaframine
92. Tremorgenic mycotoxins
93. Trichothecenes
94. Zearalenone

Section XVI: Feed and Water Contaminants
95. Melamine and cyanuric acid
96. Ionophores
97. Nonprotein nitrogen (urea) and hyperammonemia
98. Water quality and contaminants

Section XVII: Diagnostic Toxicology
99. Basic concepts of analytical toxicology
100. Sample submission for toxicological analysis
101. Toxicoproteomics in diagnostic toxicology
102. Microscopic analysis of toxic substances in feeds and ingesta

Section XVIII: Prevention and Treatment
103. Prevention and treatment of poisoning

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