Cabergoline

Cabergoline: Uses, Dosage and Side Effects

Overview

Cabergoline is a dopamine (D2) agonist with strong prolactin-specific inhibition.

Uses of Cabergoline

• Induction of oestrus.
• Control of false pregnancy in the bitch, including associated behavioral problems.
• Treatment of galactostasis in lactating bitches.
• Also used to induce abortion in bitches and queens.

Dose of Cabergoline in Dogs and Cats

Dogs:

• 5 μg (micrograms)/kg p.o. q24h for 4–6 days.
• Control of aggression-related signs may require dosing for 2 weeks.
• To induce abortion: 15 μg/kg p.o. between days 30 and 42.

Cats:

To induce abortion: 15 μg (micrograms)/kg p.o. between days 30 and 42.

Side Effects of Cabergoline in Dogs and Cats

• Vomiting or anorexia may occur.
• In some animals, a degree of drowsiness may be seen in the first 2 days of dosing.
• May induce transient hypotension.

Contraindications of Cabergoline in Dogs and Cats

• Do not use it in pregnant bitches unless the abortion is desired.
• It should not be used in combination with hypotensive drugs or in animals in a hypotensive state.

Some Notes:

• Metoclopramide antagonizes the effects on prolactin.
• Cabergoline may increase the hypotensive effects of other drugs.