Hyoscine Butylbromide

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Hyoscine Butylbromide – in Dogs and Cats : Uses, Dosage and Side Effects (Butylscopolamine, N-butylscopolammonium bromide (NBB), Butylscopolamine Bromide)

Hyoscine Butylbromide - in Dogs and Cats : Uses, Dosage and Side Effects (Butylscopolamine, N-butylscopolammonium bromide (NBB), Butylscopolamine Bromide)

Overview

  • Trade names: Buscopan
  • It inhibits M1 muscarinic acetylcholine receptors in the GI and urinary tracts causing smooth muscle relaxation but does not cross the blood-brain barrier.

Uses of Hyoscine Butylbromide

  • Control of diarrhea in dogs, particularly when pain or abdominal discomfort is present.
  • Control of pain associated with urinary obstruction in dogs.
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Dose of Hyoscine Butylbromide – Buscopan in Dogs and Cats

Dogs:

Control of diarrhea and/or abdominal discomfort:

  • 0.1 ml/ kg i.v., i.m. q12h (Buscopan Compositum).
  • 0.5 mg/kg i.m., p.o. q12h (butylscopolamine only).

Cats:

Do not use.

Drug Dosage Calculator

You Should Give:

Side Effects of Hyoscine Butylbromide in Dogs and Cats

  • Dry mouth, blurred vision, hesitant micturition, and constipation at doses acting as gut neuromuscular relaxants.
  • The i.m. route may cause a local reaction.

Contraindications of Hyoscine Butylbromide in Dogs and Cats

  • Intestinal obstruction.

Some Notes:

  • Should only be used in combination with investigations into the cause of abdominal pain or definitive relief of urinary obstruction.
  • Metamizole should not be given to dogs that have been treated with phenothiazine, as hypothermia may result.
  • Effects may be potentiated by concurrent use of other anticholinergic or analgesic drugs.
  • Metoclopramide NBB may counteract one another’s actions on GI Motility.
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