Delmadinone

Delmadinone: Uses, Dosage and Side Effects

Overview

Progestogens suppress FSH and LH production.

Uses of Delmadinone

• Treatment of hypersexuality (male dog and cat).
• Treatment of prostatic hypertrophy.
• Management of peri-anal gland adenomas.
• Treatment of hormonally driven canine aggression.

Dose of Delmadinone in Dogs and Cats

Dogs:

• Benign prostatic hypertrophy: 1.5–2 mg/kg (dogs <10 kg); 1–1.5 mg/kg (10–20 kg); 1 mg/kg (>20 kg) i.m., s.c. repeated after 8 days if no response.
• Animals that respond to treatment may need further treatment after 3–4 weeks.

Cats:

• Hypersexuality: 1.5 mg/kg repeated after 8 days if no response.
• Animals that respond to treatment may need further treatment after 3–4 weeks.

Side Effects of Delmadinone in Dogs and Cats

• Transient reduction in fertility and libido.
• Polyuria and polydipsia.
• Increased appetite.
• Hair color change at the injection site.

Contraindications of Delmadinone in Dogs and Cats

• Avoid in patients with severe renal or hepatic impairment or diabetes mellitus.

Some Notes:

• Because delmadinone has a major calming effect, dogs that show a decreased level of aggression when treated with it will not necessarily indicate the same behavioral reaction to surgical castration.
• The cortisol response to ACTH stimulation is significantly suppressed after just one dose of delmadinone.