The Common Marmoset in Captivity and Biomedical Research

By Robert Marini, Lynn Wachtman, Suzette Tardif, Keith Mansfield and James Fox

The Common Marmoset in Captivity and Biomedical Research PDF is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the American
College of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset
(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such as
macaques, but without the attendant physical and zoonotic risks.

Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. The
marmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primate
model to study a number of poorly understood disorders, like autism.

  • Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications
  • Includes contributions from renowned and international authors and editors
  • Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series
Table of Contents

Section I: BIOLOGY AND MANAGEMENT
1. Taxonomy and Natural History
2. The Anatomy of the Common Marmoset
3. Neuroanatomy of the Marmoset
4. Marmoset Nutrition and Dietary Husbandry
5. Husbandry and Housing of Common Marmosets
6. Normal Clinical and Biological Parameters of the Common Marmoset (Callithrix jacchus)
7. Behavior and Behavioral Management
8. Reproduction, Growth, and Development
9. Regulatory Considerations

Section II: DISEASES AND CLINICAL APPLICATIONS
10. Physical Examination, Diagnosis, and Common Clinical Procedures
11. Anesthesia and Common Surgical Procedures
12. Diseases of the Urogenital System
13. Diseases of the Gastrointestinal System
14. Bone, Muscle, and Skeletal Disease
15. Viral Diseases of Common Marmosets
16. Bacterial Diseases
17. Parasitic Diseases
18. Neoplastic Diseases

Section III: RESEARCH AND APPLICATIONS
19. The Genome of the Common Marmoset
20. Creating Genetically Modified Marmosets
21. Marmosets in Aging Research
22. The Marmoset Monkey as a Model for Visual Neuroscience
23. Marmosets in Neurologic Disease Research: Parkinson’s Disease
24. Experimental Autoimmune Encephalomyelitis in the Marmoset as a Translational Model for Multiple Sclerosis
25. Marmosets in Auditory Research
26. The Marmoset as a Model in Behavioral Neuroscience and Psychiatric Research
27. The Use of the Marmoset in Toxicity Testing and Nonclinical Safety Assessment Studies
28. Experimental Infections of the Common Marmoset (Callithrix jacchus)
29. Insights Gained from Marmoset Endocrine Research

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