Imidacloprid

Imidacloprid: Uses, Dosage and Side Effects

Overview

• Binds to post-synaptic nicotinic receptors resulting in paralysis and death of fleas and their larvae.

Uses of Imidacloprid

• Treatment and prevention of flea infestations in dogs and cats.

Dose of Imidacloprid in Dogs and Cats

Dogs:

• Fleas and ticks: 10 mg/kg topically every month.
• In dogs >40 kg the appropriate combination of pipettes should be applied.
• Collars should be replaced every 8 months.

Cats:

• Fleas: 10–20 mg/kg topically every month.
• Collars should be replaced every 8 months.

Side Effects of Imidacloprid in Dogs and Cats

• There may be transient itching and erythema at the site of application.
• Diazepam should be administered if the combined product with flumethrin is accidentally consumed.
• If swallowed, the spot-on product has a harsh taste and may cause salivation.
• It is possible to have transient drowsiness, irritability, and inappetence.

Contraindications of Imidacloprid in Dogs and Cats

• Do not use in unweaned puppies and kittens <8 weeks.
• The flumethrin-impregnated collar is not recommended in pregnancy and lactation and should not be used in kittens <10 weeks of age or puppies <7 weeks of age.
• Do not use the permethrin-containing product on cats.
• Moxidectin/imadocloprid is not for kittens <9 weeks, <1kg, and puppies <7 weeks.

Some Notes:

• For the treatment of flea infestations, the additional use of an approved insect growth regulator is recommended and the product should be applied every 4 weeks to all in-contact cats and dogs.
• May be used in nursing bitches and queens.
• The combined product with flumethrin or moxidectin has additional preventative and treatment indications.