Methylthioninium Chloride (Methylene blue)

Methylthioninium chloride
(Methylene blue) In Dogs & Cats: Uses, Dosage and Side Effects

Overview

• Acts as an electron donor to methaemoglobin reductase.

Uses of Methylthioninium chloride
(Methylene blue)

• Treatment of methaemoglobinaemia.
• Use an in-line filter if possible.

Dose of Methylthioninium chloride
(Methylene blue) in Dogs and Cats

Dogs:

• Methaemoglobinaemia: 1–1.5 mg/kg i.v. slowly once; it can be repeated if necessary.

Cats:

• Methaemoglobinaemia: Use with extreme caution (many consider contraindicated in this species): 1–1.5 mg/kg i.v. slowly once only.

Side Effects of Methylthioninium chloride
(Methylene blue) in Dogs and Cats

• It may cause a Heinz body haemolytic anaemia and renal failure, especially in cats (relatively contraindicated in this species).

Contraindications of Methylthioninium chloride
(Methylene blue) in Dogs and Cats

• Do not use it unless adequate renal function is demonstrated.

Some Notes: