The Laboratory Rat, 3rd Edition

The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models.  It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research.

  • New chapters on the care of surgical and fragile models and on the use of rats in research areas such as alcoholism, regenerative medicine, spinal cord injury, traumatic brain injury, and others are included.
  • All chapters were written by scientific and veterinary experts.
  • This book condenses information from many sources on topics related to the care and use of rats in research.
  • It is the premier source of information on the laboratory rat.
Table of Contents

Background of the laboratory rat
1. Historical Foundations
2. Taxonomy and Stocks and Strains
3. Translational Potential of Rats in Research

Biology and care
4. Functional Anatomy and Physiology
5. Clinical Pathology of the Rat
6. Reproduction and Breeding
7. Assisted Reproductive Technologies and Genetic Modification in Rats
8. Analysis of Behavior in Laboratory Rats
9. Nutrition
10. Housing and Environment

Clinical care and disease
11. Medical Management and Diagnostic Approaches
12. Bacterial, Mycoplasmal, and Mycotic Infections
13. Viral Disease
14. Parasitic Diseases
15. Neoplastic Disease
16. Metabolic, Traumatic, and Miscellaneous Diseases
17. Anesthesia, Analgesia, and Euthanasia
18. Care of Surgical and Other Fragile Models

Rats as research models
19. General Experimental Techniques
20. Integrating Biology with Rat Genomic Tools
21. Gnotobiotics and the Microbiome
22. Toxicology
23. Embryology and Teratology
24. Rat Immunology
25. Cardiovascular Research
26. Rat Models of Alcohol Use Disorder
27. Rat Models of Obesity, Metabolic Syndrome, and Diabetes
28. The Rate in Neuroscience Research
29. Rat Models of Central Nervous System Injury
30. Use of the Rat as a Model in Regenerative Medicine
31. Rat Models of Infectious Disease

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