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The Routledge Companion to Animal-Human History

The Routledge Companion to Animal-Human History Book PDF

The Routledge Companion to Animal-Human History

The Routledge Companion To Animal-Human History Book Pdf

By Hilda Kean, Philip Howell

The Routledge Companion to Animal-Human History Book PDF provides an up-to-date guide for the historian working within the growing field of animal-human history. Giving a sense of the diversity and interdisciplinary nature of the field, cutting-edge contributions explore the practices of and challenges posed by historical studies of animals and animal-human relationships.

Divided into three parts, the Companion takes both a theoretical and practical approach to a field that is emerging as a prominent area of study. Animals and the Practice of History considers established practices of history, such as political history, public history and cultural memory, and how animal-human history can contribute to them. Problems and Paradigms identifies key historiographical issues to the field with contributors considering the challenges posed by topics such as agency, literature, art and emotional attachment. The final section, Themes and Provocations, looks at larger themes within the history of animal-human relationships in more depth, with contributions covering topics that include breeding, war, hunting and eating.

As it is increasingly recognised that nonhuman actors have contributed to the making of history, The Routledge Companion to Animal-Human History provides a timely and important contribution to the scholarship on animal-human history and surrounding debates.

Read more: Ecological and Environmental Physiology of Mammals

More info

About Author 

Hilda Kean was Dean of Ruskin College, Oxford. Her many books include The Great Cat and Dog Massacre: The Real Story of the World War 11’s Unknown Tragedy (2017); Animal Rights: Political and Social Change in Britain since 1800 (1998); The Public History Reader (with Paul Martin, 2013).

Philip Howell is Reader in Historical Geography at the University of Cambridge. He is the author of Geographies of Regulation: Policing Prostitution in Nineteenth- Century Britain and the Empire (2009) and At Home and Astray: The Domestic Dog in Victorian Britain (2015).

Table of Contents

Introduction

1. Writing in Animals in History Philip Howell and Hilda Kean

I Animals and the Practice of History 

2. The Other Citizens: Nationalism and Animals Sandra Swart

3. New Political History and the Writing of Animal Lives Mieke Roscher 

4. Public History and Heritage: A Fruitful Approach for Privileging Animals? Hilda Kean 

5. Wildlife Conservation as Cultural Memory  Jan-Erik Steinkruger 

6. Animals in Science: Laboratory Life from the Experimental Animal to the Model Organism Robert G.W. Kirk 

7. Animals in the History of Animal and Veterinary Medicine Abigail Woods 

8. Animal Matters Liv Emma Thorsen

II Problems and Paradigms 

9. Animals, Agency, and History Philip Howell 

10. Animals in Victorian Literature and Culture Jennifer McDonnell 

11. ‘And Has Not Art Promoted Our Work Also?’ Visual Culture in Animal-Human History J. Keri Cronin 

12. When Adam and Eve were Monkeys: Anthropomorphism, Zoomorphism, and Other Ways of Looking at Animals Boria Sax 

13. Exhibiting Animals Helen Cowie 

14. Topologies of Tenderness and Violence: Human-Animal Relations in Georgian England Carl Griffin 

15. The History of Emotional Attachment to Animals Ingrid H. Tague 

16. Surviving Twentieth-Century Modernity: Birdsong and Emotions in Britain Michael Guida

III Themes and Provocations 

17. Breeding Julie-Marie Strange, Mick Worboys, and Neil Pemberton 

18. Animals in and at War Gervase Phillips 

19. Hunting and Animal-Human History Philip Howell 

20. Eating Animals Chris Otter 

21. Animals and Violence: Medieval Humanism, ‘Medieval Brutality’, and the Carnivorous Vegetarianism of Margery Kempe Karl Steel

Conclusions 

22. Practising Animal-Human History Philip Howell

Epilogue Harriet Ritvo

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Molecular Imaging of Small Animals Instrumentation and Applications

Molecular Imaging of Small Animals Instrumentation and Applications pdf

Molecular Imaging Of Small Animals Instrumentation And Applications Pdf

By Habib Zaidi

Molecular Imaging of Small Animals Instrumentation and Applications PDF examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development.

In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.

Table of Contents

Front Matter

Scintillation Detectors for Small-Animal Imaging

Solid-State Detectors for Small-Animal Imaging

Photon Detectors for Small-Animal Imaging Instrumentation

Design Considerations of Small-Animal SPECT Cameras

Design Considerations for Small Animal PET Scanners

Design Considerations of Small-Animal CT Systems

Small-Animal MRI Instrumentation

Preclinical Optical Molecular Imaging

Advances in Radiotracer Development for Molecular Imaging

Image Registration for Multimodality Small-Animal Imaging

Dual-Modality Preclinical SPECT/PET Instrumentation

Dual-Modality Preclinical SPECT/CT Instrumentation

Dual-Modality Preclinical PET/CT Instrumentation

Dual-Modality Preclinical SPECT/MRI Instrumentation

Dual-Modality Preclinical PET/MRI Instrumentation

Dual-Modality Preclinical PET-OI Concepts and Instrumentation

Quantification of Small-Animal Imaging Data

Animal Handling and Preparation for Imaging

Applications of Small-Animal Imaging in Neurology and Psychiatry

Applications of Molecular Small-Animal Imaging in Cardiology

Applications of Molecular Small-Animal Imaging in Oncology

Applications of Molecular Small-Animal Imaging in Inflammation and Infection

Applications of Small-Animal Molecular Imaging of Gene Expression

Applications of Small-Animal Molecular Imaging in Drug Development

Multimodality Molecular Imaging: A Futuristic Outlook

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Small Animal Care and Management 4th Edition

Small Animal Care and Management 4th Edition PDF

Small Animal Care And Management 4Th Edition Pdf

By Dean Warren

Small Animal Care and Management 4th Edition PDF offers a comprehensive guide to the care and husbandry of small animals. Through a logical flow of information, it introduces students to the basics of the small animal industry, including the history, safety concerns and care and welfare of these animals before diving into the specifics of each, with chapters covering dogs, cats, reptiles, birds, fish and exotic species. Full-color photos and illustrations visually depict various breeds and their characteristics, anatomy, handling techniques, housing and other care concerns to facilitate learning, while activities and additional resources offer the opportunity for application and further study.

  • Reader-friendly approach combined with a highly illustrative and engaging design facilitates learning for the student.
  • Practical information and advice, including a chapter on careers, promotes student interest and success within a specialized field of study.
  • Current topics, including a chapter on Safety as well as one on Animal Rights and Animal Welfare highlight significant concerns within the small animal industry so that students remain informed.
  • Chapter features, including “Fast Facts”, questions, activities and additional resources, enables students to validate and apply what they have learned, as well as an offer an opportunity for further study of specific areas of interest.
  • Fully supported by robust teaching and learning materials, the fourth edition includes a secure Instructor Companion site containing Lesson Plans, PowerPoint® Presentations, Testbanks powered by Cognero,and an Image Gallery, a student workbook, and a CourseMate featuring the ebook, a variety of interactivities, quizzing and more!
Table of Contents

Preface

SECTION I

CHAPTER 1 Introduction to Small Animal Care

CHAPTER 2 Safety

CHAPTER 3 Small Animals as Pets

CHAPTER 4 Animal Rights and Animal Welfare

CHAPTER 5 Careers in Small Animal Care

CHAPTER 6 Nutrition and Digestive Systems

SECTION II

CHAPTER 7 Dogs

CHAPTER 8 Cats

CHAPTER 9 Rabbits

CHAPTER 10 Hamsters

CHAPTER 11 Gerbils

CHAPTER 12 Rats

CHAPTER 13 Mice

CHAPTER 14 Guinea Pigs

CHAPTER 15 Chinchillas

CHAPTER 16 Ferrets

CHAPTER 17 Hedgehogs

CHAPTER 18 Sugar Gliders

CHAPTER 19 Amphibians

CHAPTER 20 Reptiles

CHAPTER 21 Birds

CHAPTER 22 Fish

Glossary

Appendix A: Colleges of Veterinary Medicine

Appendix B: Veterinary Technology Programs

Appendix C: Recognized Veterinary Specialty Organizations

Appendix D: Reported Cases of Lyme Disease

Glosario

Index

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Poultry Diseases, 6th Edition

Poultry Diseases, 6th Edition pdf

Poultry Diseases, 6th Edition

Poultry Diseases, 6Th Edition Pdf

By Mark Pattison, Paul McMullin, Janet Bradbury and Dennis Alexander

Now in Poultry Diseases, 6th Edition PDF, Poultry Diseases is once again fully revised with the addition of vital new material. It remains the standard reference work on health and disease for those involved in the poultry industry, government and veterinary education. Following a familiar structure, readers of the sixth edition gain concise but major reviews on current knowledge of general and disease-specific topics discussed over 45 (5 new) chapters in seven sections. With a large international team of contributors led by an authoritative editor team and a Foreword by Professor Frank Jordan, Poultry Diseases is an invaluable resource for the practicing veterinarian, poultry inspector, agricultural manager or veterinary student.

  • Covers common and rarer diseases found in all species of poultry (including chickens, ducks,
    turkeys, game birds and guinea-fowl).
  • Each chapter outside the General Overview section identifies clearly Epidemiology, Clinical
    Signs and Differential Diagnosis, Pathogenesis, Treatment and Control. Systems chapters
    discuss disorders of selected body systems in detail, leading to differential diagnosis of the
    specific disorder
  • Comprehensive Appendices of Useful Data, Glossary of Terms, and Lists of diseases specific to
    Turkeys and Ducks (cross-referenced to the disease organisms in the main text)
  • Worldwide coverage from a recognized international team of editors and contributors

Read more: Handbook on Poultry Diseases, 2nd Edition

Table of Contents
Section 1 General Overview

1. The poultry industry

2. How to carry out a field investigation

3. Laboratory investigation to support health programmes and disease diagnosis

4. Biosecurity in poultry management

5. Vaccines and Vaccination

6. Medicines and medication

7. Legislation and poultry welfare

Section 2 Bacterial Diseases

8. Enterobacteriaceae

9. Avian infections caused by species of Pasteurellaceae,Ornithobacterium and Riemerella: an introduction

10. Fowl cholera

11. Infectious coryza and related diseases

12. Gallibacterium infections and other avian Pasteurellaceae

13. Ornithobacterium rhinotracheale

14. Riemerella infections

15. Avian bordetellosis (turkey coryza)

16. Campylobacter

17. Staphylococci, streptococci and enterococci

18. Clostridia

19. Erysipelothrix rhusiopathiae – erysipelas

20. Avian mycoplasmas

21. Avian chlamydophilosis (chlamydiosis/psittacosis/ornithosis)

22. Some other bacterial diseases

Section 3 Viral Diseases

23. Herpesviridae (Marek’s disease virus, Infectious laryngotracheitis, Duck virus enteritis)

24. Retroviridae

25. Paramyxoviridae (Paramyxovirinae, Pneumovirinae)

26. Orthomyxoviridae – Avian Influenza

27. Poxviridae

28. Coronaviridae

29. Picornaviridae

30. Birnarviridae

31. Adenoviridae

32. Reoviridae (Reoviruses, Rotaviruses)

33. Astroviridae

34. Circoviridae

35. Parvoviridae

36. Caliciviridae and hepeviruses

37. Arthropod-borne viruses

Section 4 Fungal Diseases

38. Fungal diseases

Section 5 Parasitic Diseases

39. Parasitic diseases

Section 6 Diseases of Body Systems

40. Diseases of the musculoskeletal system

Section 7 Other Disorders, Poisons and Toxins

41. Practical epidemiology of poultry disease and multi-factorial conditions

42. Nutritional disorders

43. Management as a cause of disease in poultry

44. Toxicants in poultry

45. Diseases of gamebirds

Appendix: Some useful data

Index

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Cryptosporidium, Methods and Protocols

Cryptosporidium Methods and Protocols Book PDF

Cryptosporidium, Methods and Protocols

Cryptosporidium Methods And Protocols Book Pdf

By Jan R. MeadMichael J. Arrowood

Cryptosporidium Methods and Protocols Book PDF encompass broad aspects of Cryptosporidium research with established methods that have been improved and expanded over the years as well as recent cutting-edge techniques. Within this collection are numerous molecular methods as well as protocols for genotyping and diagnostics, while also including room for in vitro cell culture techniques to address the issues with growing this difficult organism continuously. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Cryptosporidium: Methods and Protocols serves as an idea guide to the inherent challenges of working with cryptosporidial parasites to provide a foundation for new investigators to build upon.

Read more: Parasitic Zoonoses

Table of Contents

About Author 

Jan R. Mead: Atlanta Veterans Affairs Medical CenterDecaturUSA

Michael J. Arrowood: Division of Foodborne, Waterborne, and Environmental DiseasesNational Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and PreventionAtlantaUSA

Table of Contents

Front Matter

Cryptosporidium Diagnostic Assays: Microscopy

Cryptosporidium Diagnostic Assays: Molecular Detection

Detection of Cryptosporidium Recovered from Large-Volume Water Samples Using Dead-
Cryptosporidium Oocyst Purification Using Discontinuous Gradient Centrifugation

Measuring Cryptosporidium Serologic Responses by Multiplex Bead Assay

Production and Purification of Functional Cryptosporidium Glycoproteins by Heterologous Expression in Toxoplasma gondii

Cryptosporidium Genotyping for Epidemiology Tracking

Use of Markers to Determine Cryptosporidium Genotypes for Epidemiology Tracking and Detection

Preparation of Cryptosporidium DNA for Whole Genome Sequencing

Accessing Cryptosporidium Omic and Isolate Data via CryptoDB.org

A Novel Method to Silence Genes in Cryptosporidium

Use of miRNAs to Study Host Cell–Parasite Interactions

Genetic Manipulation of Cryptosporidium parvum with CRISPR/Cas9

Mouse Models for Use in Cryptosporidium Infection Studies and Quantification of Parasite Burden Using Flow Cytometry, qPCR, and Histopathology

Calf Clinical Model of Cryptosporidiosis for Efficacy Evaluation of Therapeutics

Cell Culture Infectivity to Assess Chlorine Disinfection of Cryptosporidium Oocysts in Water

High-Content Screening for Cryptosporidium Drug Discovery

High-Throughput Screening of Drugs Against the Growth of Cryptosporidium parvum In Vitro by qRT-PCR

In Vitro Culture of Cryptosporidium parvum Using Hollow Fiber Bioreactor: Applications for Simultaneous Pharmacokinetic and Pharmacodynamic Evaluation of Test Compounds

In Vitro Culture of Cryptosporidium parvum Using Stem Cell-Derived Intestinal Epithelial Monolayers

Two- and Three-Dimensional Bioengineered Human Intestinal Tissue Models for Cryptosporidium

Correction to: Accessing Cryptosporidium Omic and Isolate Data via CryptoDB.org

Back Matter

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Low Stress Handling Restraint and Behavior Modification of Dogs & Cats: Techniques for Developing Patients Who Love Their Visits

Low Stress Handling Restraint and Behavior Modification of Dogs & Cats: Techniques for Developing Patients Who Love Their Visits pdf

Low Stress Handling Restraint And Behavior Modification Of Dogs &Amp; Cats: Techniques For Developing Patients Who Love Their Visits Pdf

By Sophia Yin

Low Stress Handling Restraint and Behavior Modification of Dogs & Cats: Techniques for Developing Patients Who Love Their Visits PDF. Dr. Sophia Yin, author of the Small Animal Veterinary Nerdbook, is a veterinarian, applied animal behaviorist, author, and speaker. Her passion for animals and their proper handling and restraint led her to spend hundreds of hours on this project – a new book and instructional DVD set focused on the most humane techniques that reduce stress for people and pets.

  • More than 1,600 photos that show practicing veterinarians and students how to handle dogs and cats correctly
  • Explanations of what vets think they’re doing right but may actually be doing wrong
  • Three hours of video clips with voiceover narratives that show correct and incorrect handling procedures

By using this training tool, vets will:

  • Be able to implement the most up-to-date handling techniques
  • Learn how to restrain animals correctly through behavior modification that does not involve coercion, dominance, or other negative training methods
  • Increase efficiency because patients will willingly comply with procedures
  • Stop perpetuating behavior problems in patients
  • Create a safer environment for themselves and and their team with fewer bites, scratches, and back injuries
  • Improve the bond between vet, pet, and client

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Vertebrate Skeletal Histology and Paleohistology

Vertebrate Skeletal Histology and Paleohistology PDF

Vertebrate Skeletal Histology and Paleohistology

Vertebrate Skeletal Histology And Paleohistology Pdf

By Vivian de Buffrénil, Armand J. de Ricqlès, Louise Zylberberg and Kevin Padian

Vertebrate Skeletal Histology and Paleohistology PDF summarizes decades of research into the biology and biological meaning of hard tissues, in both living and extinct vertebrates. In addition to outlining anatomical diversity, it provides fundamental phylogenetic and evolutionary contexts for interpretation. An international team of leading authorities review the impact of ontogeny, mechanics, and environment in relation to bone and dental tissues. Synthesizing current advances in the biological problems of growth, metabolism, evolution, ecology, and behavior, this comprehensive and authoritative volume is built upon a foundation of concepts and technology generated over the past fifty years.

Read more: Invertebrate Histology

Table of Contents

Foreword

Contributors

SECTION I: INTRODUCTION

1. Paleohistology: An Historical – Bibliographical Introduction

Armand J. de Ricqlès

SECTION II: MORPHOLOGY AND HISTOLOGY OF THE SKELETON

2. An Overview of the Embryonic Development of the Bony Skeleton

Vivian de Buffrénil and Alexandra Quilhac

3. The Vertebrate Skeleton: A Brief Introduction

Michel Laurin, Alexandra Quilhac and Vivian de Buffrénil

Methodological Focus A: The New Scalpel: Basic Aspects of CT-Scan Imaging

Damien Germain and Sandrine Ladevèze

4. Microanatomical Features of Bones and Their Basic Measurement

Vivian de Buffrénil, Eli Amson, Alexandra Quilhac, Dennis Voeten and Michel Laurin

Methodological Focus B: Basic Aspects of 3D Histomorphometry

Eli Amson and Damien Germain

5. Bone Cells and Organic Matrix

Louise Zylberberg

6. Current Concepts of the Mineralization of Type I Collagen in Vertebrate Tissues

William J. Landis, Tengteng Tang and Robin DiFeo Childs

7. An Overview of Cartilage Histology

Alexandra Quilhac

Methodological Focus C: Virtual (Paleo-)Histology Through Synchrotron Imaging

Sophie Sanchez, Dennis F. A. E. Voeten, Damien Germain and Vincent Fernandez

8. Bone Tissue Types: A Brief Account of Currently Used Categories

Vivian de Buffrénil and Alexandra Quilhac

Methodological Focus D: FIB-SEM Dual-Beam Microscopy for Three-Dimensional Ultrastructural Imaging of Skeletal Tissues

Natalie Reznikov and Katya Rechav

SECTION III: DYNAMIC PROCESSES IN OSSEOUS FORMATIONS

9. Basic Processes in Bone Growth

Vivian de Buffrénil and Alexandra Quilhac

10. Accretion Rate and Histological Features of Bone

Vivian de Buffrénil, Alexandra Quilhac and Jorge Cubo

11. Bone Remodeling

Vivian de Buffrénil and Alexandra Quilhac

12. Remarks on Metaplastic Processes in the Skeleton

Vivian de Buffrénil and Louise Zylberberg

SECTION IV: TEETH

13. Histology of Dental Hard Tissues

Alan Boyde and Timothy G. Bromage

SECTION V: PHYLOGENETIC DIVERSITY OF SKELETAL TISSUES

14. Introduction

Michel Laurin

15. Finned Vertebrates

Jorge Mondéjar-Fernández and Philippe Janvier

16. Early Tetrapodomorphs

Sophie Sanchez, François Clarac, Michel Laurin and Armand de Ricqlès

17. Lissamphibia

Vivian de Buffrénil and Michel Laurin

18. Early Amniotes and Their Close Relatives

Aurore Canoville, Michel Laurin and Armand de Ricqlès

19. Testudines

Torsten M. Scheyer and Ignacio A. Cerda

20. Lepidosauria

Vivian de Buffrénil and Alexandra Houssaye

21. Sauropterygia: Placodontia

Torsten M. Scheyer and Nicole Klein

22. Sauropterygia: Nothosauria and Pachypleurosauria

Torsten M. Scheyer, Alexandra Houssaye and Nicole Klein

23. Sauropterygia: Histology of Plesiosauria

P. Martin Sander and Tanja Wintrich

24. Ichthyosauria

P. Martin Sander

25. Archosauromorpha: From Early Diapsids to Archosaurs

Armand de Ricqlès, Vivian de Buffrénil and Michel Laurin

26. Archosauromorpha: The Crocodylomorpha

Vivian de Buffrénil, Michel Laurin and Stéphane Jouve

27. Archosauromorpha: Avemetatarsalia – Dinosaurs and Their Relatives

Kevin Padian and Holly N. Woodward

28. Nonmammalian Synapsids

Jennifer Botha and Adam Huttenlocker

29. Diversity of Bone Microstructure in Mammals

Vivian de Buffrénil, Christian de Muizon, Maïténa Dumont, Michel Laurin and Olivier Lambert

SECTION VI: INTEGRATIVE QUESTIONS

30. Phylogenetic Signal in Bone Histology

Jorge Cubo, Lucas J. Legendre and Michel Laurin

31. Cyclical Growth and Skeletochronology

Vivian de Buffrénil, Alexandra Quilhac and Jacques Castanet

32. Aging and Senescence Processes in the Skeleton

Catherine Bergot and Vivian de Buffrénil

33. Basic Principles and Methodologies in Measuring Bone Biomechanics

Russell P. Main

34. Interpreting Mechanical Function in Extant and Fossil Long Bones

Russell P. Main, Erin L.R. Simons and Andrew H. Lee

35. Bone Microanatomy and Lifestyle in Tetrapods

Aurore Canoville, Vivian de Buffrénil and Michel Laurin

36. Bone Histology and the Adaptation to Aquatic Life in Tetrapods

Alexandra Houssaye and Vivian de Buffrénil

37. Bone Histology and Thermal Physiology

Jorge Cubo, Adam Huttenlocker, Lucas J. Legendre, Chloé Olivier and Armand de Ricqlès

38. Bone Ornamentation: Deciphering the Functional Meaning of an Enigmatic Feature

François Clarac

39. The Histology of Skeletal Tissues as a Tool in Paleoanthropological and Archaeological Investigations

Ariane Burke and Michelle S. M. Drapeau

40. A Methodological Renaissance to Advance Perennial Issues in Vertebrate Paleohistology

Alexandra Houssaye, Donald Davesne and Aurore Canoville

Extended Table of Contents

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Toxicologic Pathology, Nonclinical Safety Assessment, 2nd Edition

Toxicologic Pathology, Nonclinical Safety Assessment 2nd Edition PDF

Toxicologic Pathology, Nonclinical Safety Assessment, 2nd Edition

Toxicologic Pathology, Nonclinical Safety Assessment 2Nd Edition Pdf

By Pritam S. Sahota, James A. Popp, Jerry F. Hardisty, Chirukandath Gopinath and Page Bouchard

Toxicologic Pathology, Nonclinical Safety Assessment, 2nd Edition PDF is designed to provide practical and timely information for toxicologic pathologists working in pharmaceutical drug discovery and development. The majority of the book (Organ Systems) will provide detailed descriptions of histopathological lesions observed in drug development. In addition, it will provide information to assist the pathologist in making determinations of the origin of lesions as well as its relevance to human risk.

Toxicologic Pathology: Nonclinical Safety Assessment, Second Edition includes 2 new concept chapters. The first of the new chapters address approaches for the evaluation of unique therapeutic modalities such as cell therapies, gene therapies, and gene expression knockdown therapies. While these still represent new developing therapeutic approaches, there has been significant experience with the therapeutic modalities in the last 5 years. The second new chapter addresses the nonclinical safety assessment of medical devices, a topic of increasing importance that was not addressed in a unique chapter in the first edition. The other concept chapters have been updated and cover important topics including the overview of drug development; principles of nonclinical safety assessment; an introduction to toxicologic pathology; techniques used in toxicologic pathology, clinical pathology, toxicokinetics, and drug development toxicogenomics; and spontaneous lesions.

The 13 organ system chapters provide the specifics related to pathologic characteristics, differential diagnosis, and interpretation of toxic responses in each organ system. These chapters are specifically important for the bench pathologist but also for the toxicologist who interacts with pathologists and function as study toxicologists and project team representatives in the drug development arena.

Read more: Veterinary Toxicology, Basic and Clinical Principles, 3rd Edition

Table of Contents

Preface

Acknowledgments

Editors

Contributors

Section I Concepts in Drug Development

Chapter 1 Overview of Drug Development

James A. Popp and Jeffery A. Engelhardt

Chapter 2 Nonclinical Safety Evaluation of Drugs

Thomas M. Monticello and Jeanine L. Bussiere

Chapter 3 Nonclinical Safety Evaluation of Advanced Therapies

Timothy K. MacLachlan, Kendall S. Frazier, and Mercedes Serabian

Chapter 4 Nonclinical Safety Evaluation of Medical Devices

Kathleen A. Funk, Victoria A. Hampshire, and JoAnn C. L. Schuh

Chapter 5 Pathology and the Pathologist in Pharmaceutical Research and Development

Page R. Bouchard, Christopher J. Clarke, and Dominique Brees

Chapter 6 Routine and Special Techniques in Toxicologic Pathology

Daniel J. Patrick, Matthew L. Renninger, and Peter C. Mann

Chapter 7 Principles of Clinical Pathology

Niraj K. Tripathi and Jacqueline M. Tarrant

Chapter 8 Toxicokinetics and Drug Disposition

David D. Christ

Chapter 9 Toxicogenomics in Toxicologic Pathology

Arun R. Pandiri, David E. Malarkey, and Mark J. Hoenerhoff

Chapter 10 Spontaneous Lesions in Control Animals Used in Toxicity Studies

Robert C. Johnson, Robert H. Spaet, Gitte Jeppesen, Ursula Junker, and Robert Stull

Section II Organ Systems

Chapter 11 Gastrointestinal Tract

Judit E. Markovits, Graham R. Betton, Donald N. McMartin, and Theresa Boulineau

Chapter 12 Liver, Gallbladder, and Exocrine Pancreas

Russell C. Cattley, James A. Popp, and Steven L. Vonderfecht

Chapter 13 Respiratory System

Tom P. McKevitt and David J. Lewis

Chapter 14 Urinary System

Kendall S. Frazier and John Curtis Seely

Chapter 15 Hematopoietic System

Kristin Henson, Tanasa Osborne, and Gregory S. Travlos

Chapter 16 The Lymphoid System

Patrick J. Haley

Chapter 17 Bone, Muscle, and Tooth

John L. Vahle, Joel R. Leininger, Philip H. Long, D. Greg Hall, and Heinrich Ernst

Chapter 18 The Cardiovascular System

Calvert Louden, David Brott, Chidozie J. Amuzie, Bindu Bennet, and Ronnie Chamanza

Chapter 19 Endocrine Glands

Richard A. Peterson, Sundeep Chandra, and Mark J. Hoenerhoff

Chapter 20 Reproductive System and Mammary Gland

Justin D. Vidal, Charles E. Wood, Karyn Colman, Katharine M. Whitney, and Dianne M. Creasy

Chapter 21 Skin

Zbigniew W. Wojcinski, Lydia Andrews-Jones, Daher Ibrahim Aibo, Rie Kikkawa, and Robert Dunstan

Chapter 22 Nervous System

Mark T. Butt, Alys Bradley, and Robert Sills

Chapter 23 Special Senses: Eye and Ear

Kenneth A. Schafer, Oliver C. Turner, and Richard A. Altschuler

Index

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The Grief Recovery Handbook for Pet Loss

The Grief Recovery Handbook for Pet Loss pdf

The Grief Recovery Handbook For Pet Loss Pdf

By Russell Friedman, Cole James and John W. James

The Grief Recovery Handbook for Pet Loss PDF. If you’ve found yourself almost inconsolable after your pet died, please know that you’re normal.

If you’ve found that your family and friends don’t seem to understand the level of your grief, please know that, too, is normal.

Without comparing our relationships with our pets to those with people, we know that, because of the unique emotional relationships we have with our pets, their deaths produce a level of pain that is difficult to describe.

If you relate to any or all of these sentences, this book is for you.

We have been there and most probably will be there again. We will be with you on this journey to help your heart deal with the absence of your cherished companion.

Table of Contents

Introduction: millions of pet deaths every year but very little effective help

Don’t feel bad, it was only a ..

Four major myths that limit us, and more

Short-term energy relieving behaviors (STERBs)

Your history of pet losses

Preparing to review the relationship

The relationship graph

Converting your relationship graph into recovery categories

Apologies

The grief recovery method completion letter?

More to do? maybe!

Conclusionary rituals

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Horse Movement: Structure, Function and Rehabilitation

Horse Movement: Structure, Function and Rehabilitation pdf

Horse Movement: Structure, Function And Rehabilitation Pdf

By Gail Williams and Alexa McKenna

Anatomy is often said to be boring, but nothing could be further from the truth. Anatomy, particularly functional anatomy, is a vital and dynamic subject, an appreciation of which leads not only to superior husbandry and welfare, but also to a better understanding of the anatomical challenges associated with riding, training, overtraining, injury and rehabilitation.

Using Alexa McKenna’s fabulous illustrations, Horse Movement: Structure, Function and Rehabilitation PDF shows the correlation of the skeleton, muscular system and locomotion, providing a clear insight into the functional and dysfunctional horse. It also addresses the largely misunderstood concept of ‘perfect conformation’and looks at the effect on function of the rider and tack, using cutting-edge diagnostic techniques such as thermal imaging and gait analysis.

Again with the emphasis on the visual, readers will be able to appreciate how muscles function in differing athletic disciplines by analysing the heat generated in musculoskeletal structures after exercise. This will also highlight the importance of post-competition recovery. Horse Movement: Structure, Function and Rehabilitation concludes with a range of useful techniques to improve the function of any horse, including stretches, taping, wrapping and other proprioceptive techniques to increase balance, flexibility, awareness and posture.

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