Animal Models in Cardiovascular Research

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Animal Models in Cardiovascular Research

Animal Models In Cardiovascular Research Pdf

By David Gross

Animal Models in Cardiovascular Research PDF describes historical and recent advances in our understanding of the cardiovascular system from studies conducted in a variety of animal models. Since the last edition, we have witnessed an explosion in the use of both congenic and transgenic animals. The use of specific knock-in and knock-out transgenic models has resulted in an avalanche of genetic, molecular, and protein-based information that, potentially, could result in an amazing new array of treatment and management options. However, the results of these studies also introduce a sometime bewildering array of redundant, overlapping, and competing molecular pathways involved in both physiological and pathological responses.

This third edition is designed to provide a better basis for understanding and using animal models in the current climate of background knowledge and information. It is significantly different than the previous two editions. Chapter 1 is updated from the previous editions addressing general principles of animal selection. It also provides expanded tables of normal physiological values for easy reference.

Read more: Animal Models and Human Reproduction

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