The Laboratory Guinea Pig, 2nd Edition

Features:

• Includes drug dosage and anesthetic protocols, and tables of normative biological data
• Details basic information for animal facility management, animal husbandry, regulatory compliance, and technical procedures
• Illustrates key concepts and procedures with more than 50 color illustrations
• Offers sources and suppliers of animals, feed, sanitation supplies, cages, and research and veterinary supplies
• Comb-bound for quick and easy access by investigators, technicians, and animal caretakers

Table of Contents:

1. Important Biological Features

• Introduction

• Breeds

• Behavior

  • Individual Behavior

  • Social Behavior and Communication

  • Aggression and Reproductive Behavior

• Anatomic and Physiologic Features

  • External Anatomy

  • Dentition

  • Skeletal System

  • Hemolymphatic System

  • Gastrointestinal System

  • Respiratory System

  • Urogenital System

  • Miscellaneous Unique Physiologic Features and Normative Values

  • Hematology

  • Cardiovascular and Respiratory Function

  • Miscellaneous Physiologic and Anatomic Features

  • Reproduction

2. Husbandry

• Housing

• Environmental Conditions

• Environmental Enrichment

• Nutrition

• Sanitation

• Transportation

• Record Keeping

3. Management

• Regulatory Agencies and Compliance

  • USDA

  • NIH / PHS

  • FDA and EPA

  • AAALAC International

• Institutional Animal Care and Use Committee (IACUC)

• Occupational Health and Zoonotic Diseases

• Animal Health Monitoring Program

4. Veterinary Care

• Basic Veterinary Supplies

• Physical Examination of the Guinea Pig

• Quarantine

• Clinical Signs of Illness

• Common Clinical Problems

  • Vitamin C Deficiency (Scurvy)

  • Bordetella bronchiseptica

  • Streptococcus pneumoniae

  • Cervical Lymphadenitis

  • Antibiotic Toxicity

  • Pregnancy Toxemia

  • Salmonellosis

  • Alopecia

  • Malocclusion

  • Protozoal Diseases

  • Viral Diseases

  • Pododermatitis

  • Conjunctivitis

• General Treatment of Disease

• Disease Prevention through Sanitation

• Anesthesia and Analgesia

  • Principles of General Anesthesia

  • Characteristics of Commonly Used Injectable Anesthetics

  • Principles of Gas Anesthesia

  • Characteristics of Commonly Used Gas Anesthetics

  • Principles of Local Anesthesia

  • Sedation and Tranquilization

  • Analgesia

  • Perianesthetic Management

  • Aseptic Surgery

  • Postsurgical Management

• Euthanasia

5. Experimental Methodology

• Restraint

  • Manual Restraint

  • Restraint Devices

• Sampling Techniques

  • Blood Collection

  • Urine Collection

  • Milk Collection

• Compound Administration Techniques

  • Intravascular (IV)

  • Intramuscular (IM)

  • Subcutaneous (SC)

  • Intraperitoneal (IP)

  • Intradermal (ID)

  • Oral (PO)

  • Intracerebroventricular

  • Aural—Inner Ear

• Adjuvants

• Safety Testing Procedures

  • Magnusson Maximization Test

  • Buehler Closed-Patch Sensitization Test

  • Guinea Pig Antigenicity (Anaphylaxis) Test

  • Sereny Test

• Necropsy

6. Resources

• Organizations

• Publications (Books, Periodicals)

• Online Resources

• Animal Sources

• Feed

• Equipment

• Possible Sources of Cages and Research/Veterinary Supplies

• Commercial Laboratories for Animal Health Monitoring

References