Pantoprazole

Pantoprazole In Dogs & Cats: Uses, Dosage and Side Effects

Overview

• It reduces gastric acid secretion, under both basal and stimulated conditions.
• Pharmacological action can last >24 hours.

Uses of Pantoprazole

• Management of gastric and duodenal ulcers, oesophagitis, and hypersecretory conditions secondary to gastrinoma (Zollinger–Ellison syndrome) or mast cell neoplasia.

Dose of Pantoprazole in Dogs and Cats

Dogs, Cats:

• All uses: 0.7–1.0 mg/kg i.v. over 15 min q24h.
• Oral dose not established in cats/dogs but likely similar to i.v. dose.

Side Effects of Pantoprazole in Dogs and Cats

• It appears well tolerated. Adverse effects in humans include diarrhoea, headache, hyperglycaemia (rare), and an increased risk of pneumonia.
• Thrombophlebitis has been associated with i.v. injection.

Contraindications of Pantoprazole in Dogs and Cats

• Do not give i.m. or s.c.

Some Notes:

• May affect the absorption of drugs requiring low gastric pH for absorption, e.g. itraconazole, and ketoconazole.