Chitosan: Uses, Dosage and Side Effects
Overview
Adsorbent for intestinal uraemic toxins, including phosphate.
Uses of Chitosan
- Reduce serum urea and phosphate in chronic renal disease in cats.
- Phosphate-binding agents are usually only used if low-phosphate diets are unsuccessful.
- Monitor serum phosphate levels at 4–6 week intervals and adjust dosage accordingly if trying to achieve target serum concentrations.
- Monitor for hypercalcaemia.
- As the formulation contains lactose, use it with care in diabetic and lactose-intolerant animals.
Dose of Chitosan in Dogs and Cats
Dogs, Cats:
Chronic kidney disease: 200 mg/kg p.o. q12h (mixed with food)
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Side Effects of Chitosan in Dogs and Cats
Hypercalcaemia, possibly due to the calcium carbonate component.
Contraindications of Chitosan in Dogs and Cats
None reported.
Some Notes:
Increased risk of hypercalcemia with concurrent calcitriol administration.
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