The Toxicology of Fishes. When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution on these organisms has been widely available, until now. Filling this void, The Toxicology of Fishes, written by recognized experts, covers toxic responses ranging from reduced reproduction and/or abnormal development, growth, and differentiation.
General Principles โ Discusses fundamental topics such as the bioavailability of chemicals present in the aquatic environment to fishes, processes governing chemical distribution within these organisms, how fish metabolize organic chemicals, and fundamental mechanisms of chemical toxicity
Key Target Systems and Organismal Effects โ Describes key target organ systems for chemical impacts in fish, how chemicals produce cancer in these animals, and how fishes can develop resistance to chemical toxicity
Methodologies and Applications โ Dovers methods for the assessment of chemical effects on fish such as toxicity tests, biomarkers, simulated ecosystems, and modeling approaches and the use of data from such studies in ecological risk assessments
Case Studies โ Provides examples of how the principles and approaches presented in earlier units are actually deployed in studies
Illustrated by case studies of actual, large-scale field investigations, the book reviews the tools used to assess unwanted effects in laboratory model- and wild fish in detail. With 238 illustrations, 70 tables, and 50 equations, this comprehensive monograph presents detailed information on the boiavailability of chemical pollutants, their distribution, metabolism, and excretion in the host fish and mechanisms and sites of toxic responses.
Provides in-depth coverage that ranges from the molecular level to the community and population level
Covers the interaction of chemical contaminants with freshwater and marine fishes
Presents case studies that give insight into the effects of chemical classes perturbing aquatic systems
Explores the interplay of feedback between controlled laboratory experiments and field investigations
Table of Contents
Table of Contents:
Introduction
Bioavailability of Chemical Contaminants in Aquatic Systems
Toxicokinetics in Fishes
Biotransformation in Fishes
Receptor-Mediated Mechanisms of Toxicity
Reactive Oxygen Species and Oxidative Stress
Key Target Systems and Organismal Effects
Liver Toxicity
Toxic Responses of the Fish Nervous System
The Endocrine System
The Immune System of Fish: A Target Organ of Toxicity
Toxicity Resistance
Methodologies and Applications 13. Exposure Assessment and Modeling in the Aquatic Environment 14. Fish Toxicity Studies 15. Biomarkers 16. Aquatic Ecosystems for Ecotoxicological Research: Considerations in Design Analysis for Fish 17. Ecological Risk Assessment
Case Studies 18. Mining Impacts on Fish in the Clark Fork River, Montana: A Field Ecotoxicology Case Study 19. Toxicology of Synthetic Pyrethroid Insecticides in Fish: A Case Study 20. Reproductive Impairment of Great Lakes Lake Trout by Dioxin-Like Chemicals 21. The Effects of Polycyclic Aromatic Hydrocarbons in Fish from Puget Sound 22. Effects of the Exxon Valdez Oil Spill on Pacific Herring in Prince William Sound 23. Case Study: Pulp and Paper Mill Impacts 24. Estrogenic Effects of Treated Sewage Effluent on Fish: Steroids and Surfactants in English Rivers
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