Organic Synthesis Smith 3rd Edition PDF. A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined.
To save students much time catching up this text provides a reliable and readily available source for background material that will enable all graduate students to reach the same high level of proficiency in organic chemistry. Produced over many years with extensive feedback from students taking an organic chemistry course this book provides a reaction based approach. The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to ‘disconnect’ a bigger molecule into simpler building blocks.
Most chapters include an extensive list of questions to test the reader’s understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists.
Organic Synthesis Smith 3rd Edition PDF book is intended for graduate and postgraduate students, scientific researchers in chemistry
Table of Contents
Organic Synthesis Smith 3rd Edition Contents
Front matter
Copyright
About the Author
Preface to the 3rd edition
Preface to the 1st edition.
abbreviations
Chapter 1 – Retrosynthesis, Stereochemistry, and Conformations
Chapter 2 – Acids, Bases and Functional Group Exchange Reactions
Chapter 3 – Oxidation
Chapter 4 – Reduction
Chapter 5 – Hydroboration
Chapter 6 – Stereocontrol and Ring Formation
Chapter 7 – Protecting Groups
Chapter 8 – Cd Disconnect Products: Nucleophilic Species that Form Carbon-Carbon Bonds
Chapter 9 – Cd Disconnect Products: Nucleophilic Species that Form Carbon-Carbon Bonds:
Chapter 10 – Synthetic Strategies
Chapter 11 – Pericyclic carbon-carbon Bond Forming reactions: Multiple Bond
Chapter 12 – Ca Disconnect Products: Electrophilic Carbon-Carbon Bond-Forming Reactions
Chapter 13 – Carbon Radical Disconnect Products: Formation of Carbon-Carbon Bonds via
Chapter 14 – Student Synthesis: The First Synthetic Problem
