Handbook of Mouse Mutations with Skin and Hair Abnormalities PDF

Handbook Of Mouse Mutations With Skin And Hair Abnormalities Pdf Download

By John P. Sundberg

Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects.

Handbook of Mouse Mutations with Skin and Hair Abnormalities book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.

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Table of Contents

Table of Contents:

Biology of Skin and Hair of Laboratory Mice and Human Beings: Introduction. Applications and Needs of Models for Dermatological Research
Inbred Laboratory Mice as Animal Models and Biomedical Tools: General Concepts
The Jackson Laboratory Mouse Mutant Resource
Hair Follicle Stem Cells
The Mouse Skin as a Model for Chemical Carcinogenesis
Viral-Induced Skin Tumors in Mice
Hair Types and Subtypes in the Laboratory Mouse
Growth Factors and Cutaneous Pathology
Transgenic Mice with Cytokine Mutations Affecting the Skin
Epidermal Keratins
Hair Follicle Keratins
Keratinocyte Cultures as Models for Dermatologic Disease
Mouse Mutations with Endocrine Functional Consequences
The Immune System in Cutaneous Disease: The Search for a Mouse Model of the Immunopathology of Psoriasis
Animal Models of Genetic Based Skin Diseases: Mouse Single Gene Mutations: Introduction
The Adrenocortical Dysplasia (acd) Mutation, Chromosome 8
The Angora (go) Mutation, Chromosome 5
The Asebia (ab, abJ) Mutations, Chromosome 19
The Atrichosis (at) Mutation, Chromosome 10
The Balding (bal) Mutation, Chromosome 18
The Bare-Patches (Bpa) Mutation, Chromosome X
The Bareskin (Bsk) Mutation, Chromosome 11
The Beige (bg) Mutation, Chromosome 13
The Caracul (Ca and Cad) Mutations, Chromosome 15
The Chronic Proliferative Dermatitis (cpd) Mutation, Chromosome ?
The Crinkled (cr) Mutation, Chromosome 13
The Curly-Whiskers (cw) Mutation, Chromosome 9
The Depilated (dep) Mutation, Chromosome 4
The Downless (dl) and Sleek (Dlslk) Mutations, Chromosome 10
The Ferrochelatase Deficiency (Fechm1Pas) Mutation, Chromosome 18
The Flaky Skin (fsn) Mutation, Chromosome ?
The Flaky Tail (ft) Mutation, Chromosome 3
The Frizzy (fr) Mutation, Chromosome 7
The Fuzzy Mutation (fz), Chromosome 1
The Greasy (Gs) Mutation, Chromosome X
The Hair Interior Defect (hid) Mutation, Chromosome ?
The Hairless (hr) and Rhino (hrrh) Mutations, Chromosome 14
The Hair Patches (Hpt) Mutation, Chromosome 4
The Hairy Ears (Eh) Mutation, Chromosome 15
The Harlequin (Hq) Mutation, Chromosome X
The Ichthyosis (ic) Mutation, Chromosome 1
The Lethal Milk (lm) Mutation, Chromosome 2
The Lustrous (lt) Mutation, Chromosome 11
The Matted (ma) Mutation, Chromosome 3
The Motheaten (me) and Viable Motheaten (mev) Mutations, Chromosome 6
The Mottled Locus: Mottled (Mo), Blotchy (Moblo), Brindled (Mobr), Dappled (Modp), Mosaic (Moms), Tortoiseshell (Moto), and Viable Brindled (Movbr) Mutations, Chromosome X
The Naked (N) Mutation, Chromosome 15
The Nude (nu) and Streaker (nustr) Mutations, Chromosome 11
The Ragged (Ra) and Opossum (Raop) Mutations, Chromosome 2
The Repeated Epilation (Er) Mutation, Chromosome 4
The Rex (Re), Wavy Coat (Rewc), and Denuded (Reden) Mutations, Chromosome 11
The Satin (sa) Mutation, Chromosome 13
The Scurfy (sf) Mutation, Chromosome X
The Severe Combined Immunodeficiency (scid) Mutation, Chromosome 16
The Shaven (Sha) Mutation, Chromosome 15
The Silver (si) Mutation, Chromosome 10
The Soft Coat (soc) Mutation, Chromosome 3
The Sparse-Coat (spc) Mutation, Chromosome 14
The Sparse-Fur (Otcspf) and Abnormal Skin and Hair (Otcash) Mutations, Chromosome X
The Tabby (Ta), Tabby-c (Tac), and Tabby-J (TaJ) Mutations, Chromosome X
The Tight-Skin (Tsk) Mutation, Chromosome 2
The Vitiligo (mivit) Mutant Allele of the Microphthalmia Locus, Chromosome 6
The Wellhaarig (we, weBkr) Mutations, Chromosome 2
Purported Polygenic Mouse Skin Diseases: Introduction
Chronic Ulcerative Dermatitis in Black Mice
Barbering Behavioral Abnormalities in Inbred Laboratory Mice
Alopecia Areata in Aging C3H/HeJ Mice
Nonmurine Animal Models of Genetic Based Skin Diseases: Introduction
Selected Heritable Skin Diseases of Domesticated Animals