Pyrantel

Pyrantel In Dogs & Cats: Uses, Dosage and Side Effects

Overview

• A cholinergic agonist which interferes with neuronal transmission in parasites and thereby kills them.
• Febantel and oxantel derivatives of pyrantel with increased activity against whipworms.

Uses of Pyrantel

• Control of Toxocara canis, Toxascaris leonina, Trichuris vulpis, Uncinaria stenocephala, and Ancylostoma caninum.

Dose of Pyrantel in Dogs and Cats

Dogs:

• 5 mg/kg pyrantel + 15 mg/kg febantel or 20 mg/kg oxantel p.o., repeat as required.

Cats:

• 57.5 mg/kg pyrantel embonate.

Side Effects of Pyrantel in Dogs and Cats

• Vomiting and diarrhoea may be observed.

Contraindications of Pyrantel in Dogs and Cats

• Do not use in puppies <2 months or <1 kg.
• Safety has not been established in pregnant or lactating animals and therefore its use is not recommended.

Some Notes:

• The addition of febantel or oxantel has a synergistic effect.
• Do not use with levamisole, piperazine or cholinesterase inhibitors.