Ofloxacin

Ofloxacin In Dogs & Cats: Uses, Dosage and Side Effects

Overview

• Concentration-dependent antimicrobial which works by inhibiting the bacterial DNA gyrase enzyme, causing damage to the bacterial DNA.

Uses of Ofloxacin

• Fluoroquinolone usage should be reserved for cases where culture and sensitivity testing indicate a likely clinical response and when conventional first- and second-line antimicrobial treatments would not be effective.
• It is particularly useful for ophthalmic applications when other antibacterial drugs prove ineffective.
• Fluoroquinolones demonstrate activity against various ocular pathogens, including Staphylococcus and Pseudomonas aeruginosa, although some staphylococcal and streptococcal organisms are becoming increasingly resistant.
• Notably, they exhibit better penetration of the cornea compared to ciprofloxacin.

Dose of Ofloxacin in Dogs and Cats

Dogs, Cats:

• 1 drop to affected eye q6h
• Intensive therapy q30–120min for short-term use (1–2 days).

Side Effects of Ofloxacin in Dogs and Cats

• May cause local irritation after application.

Contraindications of Ofloxacin in Dogs and Cats

• No information is available.