Imidocarb Dipropionate

Imidocarb Dipropionate In Dogs & Cats:: Uses, Dosage and Side Effects

Overview

• Interferes with the metabolic process of nucleic acids in parasites.

Uses of Imidocarb dipropionate

• Treatment of Babesia canis infection in dogs.

Dose of Imidocarb dipropionate in Dogs and Cats

Dogs:

• Treatment of Babesia canis infection: 6.6 mg/kg imidocarb dipropionate i.m., s.c. once, repeated in 2–3 weeks.
• The dose should be calculated based on Imizol containing 121.15 mg/ml imidocarb
  dipropionate.
• Premedication with atropine (0.05 mg/kg) to minimize side effects could be considered.

Cats:

• Treatment of Babesia canis infection: 2.5 mg/kg imidocarb dipropionate i.m. once can improve clinical signs in cats infected with large babesial species.
• The dose should be calculated based on Imizol containing 121.15 mg/ml imidocarb dipropionate.
• Alternative agents are preferable for smaller species (e.g. Babesia felis); however,
  the parasitological cure is rare and controlled therapeutic trials are lacking.

Side Effects of Imidocarb dipropionate in Dogs and Cats

• After a dose, cholinergic signs like salivation, vomiting, and sometimes diarrhoea, panting, and nervousness can happen.
• Atropine might help with these signs.
• Mild irritation at the injection site has been reported to last from one to several days and may lead to sores.
• Cattle have been known to have anaphylactoid responses, but dogs have not.

Contraindications of Imidocarb dipropionate in Dogs and Cats

• Do not administer i.v.

Some Notes:

• Avoid concurrent use of anticholinesterases.