Meglumine Antimonate

Meglumine Antimonate In Dogs & Cats: Uses, Dosage and Side Effects

Overview

• Reported to interfere with the glucose metabolism of Leishmania parasites.

Uses of Meglumine antimonate

• Treatment of canine leishmaniosis

Dose of Meglumine Antimonate in Dogs and Cats

Dogs:

• Leishmaniosis: 75–100 mg/kg s.c. q24h or 40–75 mg/kg s.c. q12h until clinical remission is achieved.
• Treat for at least 28 days.

Cats:

• No information is available.

Side Effects of Meglumine Antimonate in Dogs and Cats

• Pain at the injection site has been reported.

Contraindications of Meglumine Antimonate in Dogs and Cats

• Do not use where severe liver dysfunction, renal dysfunction or heart disease exists.

Some Notes:

• Care with agents that can also cause QT interval prolongation.
• Animals may be clinically normal after treatment but the parasitological cure is extremely difficult to achieve.
• Concurrent treatment with allopurinol may be appropriate depending on the disease severity/clinical condition.