Chlortetracycline Hydrochloride

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Chlortetracycline Hydrochloride: Uses, Dosage and Side Effects

Chlortetracycline Hydrochloride

Overview

1st generation time- and concentration-dependent antimicrobial that inhibits bacterial protein synthesis by binding to the 30S subunit of the bacterial ribosome.

Uses of Chlortetracycline hydrochloride

  • Treatment of feline chlamydial conjunctivitis (oral doxycycline is the treatment of choice).
  • Treatment of mycoplasmal conjunctivitis and canine spontaneous chronic corneal epithelial defects (via an immunomodulatory mechanism).
  • Treatment of keratitis, conjunctivitis, and blepharitis caused by Staphylococcus spp., Streptococcus spp., and Proteus spp. and/or Pseudomonas spp.
  • Tetracyclines have a broad spectrum including both aerobic and anaerobic Gram-positive and Gram-negative bacteria, mycoplasmas, rickettsiae, and Chlamydia spp. Pseudomonas spp. and Staphylococci spp. may be resistant.
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Dose of Chlortetracycline hydrochloride in Dogs and Cats

Dogs and cats:

0.5–2 cm of ointment to affected eye q6h for 5 days.

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Side Effects of Chlortetracycline hydrochloride in Dogs and Cats

None known

Contraindications of Chlortetracycline hydrochloride in Dogs and Cats

Safety during pregnancy and lactation is unknown.

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