Antineoplastic

Rabacfosadine In Dogs & Cats: Uses, Dosage and Side Effects Overview Prodrug of the nucleotide analogue PMEG; causes cytotoxicity in dividing cells due to inhibition...

Melphalan In Dogs & Cats: Uses, Dosage and Side Effects Overview Forms inter- and intrastrand cross-links with DNA, resulting in inhibition of DNA synthesis and...

Osaterone In Dogs & Cats: Uses, Dosage and Side Effects Overview Competitively prevents the binding of androgens to their prostatic receptors and blocks the transport...

Mitoxantrone In Dogs & Cats: Uses, Dosage and Side Effects Overview Antitumour antibiotic which inhibits topoisomerase II. It is cell cycle non-specific, but most active...

Methotrexate In Dogs & Cats: Uses, Dosage and Side Effects Overview This compound is an antimetabolite antineoplastic agent that specifically targets the S-phase of the...

Masitinib Mesylate In Dogs & Cats: Uses, Dosage and Side Effects Overview In vitro selective and potent protein tyrosine kinase inhibitor with maximal affinity for...

Lomustine (CCNU) In Dogs & Cats: Uses, Dosage and Side Effects Overview Interferes with the synthesis and function of DNA, RNA and proteins. Antitumour activity...

Hydroxycarbamide (Hydroxyurea): Uses, Dosage and Side Effects Overview It inhibits ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides (important precursors for DNA synthesis and repair). It...

Gemcitabine in Dogs and Cats: Uses, Dosage and Side Effects Overview Metabolites of the drug inhibit the enzyme ribonucleotide reductase and compete with endogenous nucleotides...

Fluorouracil (5-FU): Uses, Dosage and Side Effects Overview Fluorouracil's metabolites stop the production of pyrimidine, which blocks DNA from being synthesised and stops it from...