Oxybutynin hydrochloride In Dogs & Cats: Uses, Dosage and Side Effects
Overview
- Works as a urinary antispasmodic with antimuscarinic and spasmolytic effects on smooth muscle.
Uses of Oxybutynin hydrochloride
- May be useful for the treatment of detrusor hyperreflexia/ overactive bladder in cats and dogs.
Dose of Oxybutynin hydrochloride in Dogs and Cats
Dogs:
- Detrusor hyperreflexia (refractory incontinence): 0.2 mg/kg p.o. q8–12h.
Cats:
- Detrusor hyperreflexia: 0.5–1.25 mg per cat p.o. q8–12h.
Drug Dosage Calculator
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Side Effects of Oxybutynin hydrochloride in Dogs and Cats
- Small animals have experienced side effects like diarrhea, constipation, urinary retention, and sedation when using this medication.
- In humans, reported adverse effects include dryness of the mouth and eyes, skin reactions, rapid heart rate, vomiting, palpitations, and confusion.
Contraindications of Oxybutynin hydrochloride in Dogs and Cats
- Limited animal data but in humans contraindications include obstructive GI disease/ileus, gastro-oesophageal reflux/hiatal hernia, glaucoma, cardiac disease,
myasthenia gravis and obstructive urinary disease.
Some Notes:
- Use with caution in patients receiving other anticholinergic agents, azole antifungals, CNS depressants and macrolide antibiotics.
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