Tuberculosis, Leprosy and Mycobacterial Diseases of Man and Animals, The Many Hosts of Mycobacteria
By Harshini Mukundan, Mark Chambers, Ray Waters and Michelle Larsen
Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book will provide a reference for researchers working in different fields creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.
Table of Contents
Introduction:
The Many Hosts of Mycobacteria:
An Interdisciplinary Approach to Understanding Mycobacterial Diseases
Part I: Tuberculosis in Humans
1: Introduction and Epidemiology of Mycobacterium tuberculosis Complex in Humans
2: Comparative Mycobacteriology of the Mycobacterium tuberculosis Complex
3: Immunopathogenesis of Tuberculosis in Humans
4: Current Methods for Diagnosis of Human Tuberculosis and Considerations for Global Surveillance
5: Development of Next-generation TB Vaccines: Comparative Approaches in Humans and Animals
6: The Continuing Co-evolution of Mycobacterium tuberculosis and Homo sapiens
Part II: Tuberculosis in Domesticated and Companion Animal Species
7: The Global Distribution of Mycobacterium bovis
8: Immunopathogenesis of Mycobacterium bovis Infection of Cattle
9: Diagnosis of Mycobacterium bovis Infection in Cattle
10: Vaccination of Cattle Against Tuberculosis
11: Mycobacterium bovis/M. caprae Infection in Goats and Sheep: Introduction, Epidemiology and Control Measures
12: Mycobacterial Infections in Camelids
13: Tuberculosis in Companion Animal Species
Part III: Mycobacterial Infections in Zoo Species
14: Mycobacterial Infections in Elephants
15: Mycobacterial Infections in Other Zoo Animals
Part IV: Tuberculosis in Wildlife
16: Tuberculosis in Badgers (Meles meles)
17: Tuberculosis in Pigs and Wild Boar
18: Australian Brushtail Possum: A Highly Susceptible Host for Mycobacterium bovis
19: Tuberculosis in Wild and Captive Deer
20: Tuberculosis in South African Wildlife: Lions, African Buffalo and Other Species
21: Novel Mycobacterium tuberculosis Complex spp. in Group-living African Mammals
Part V: In Vivo Laboratory Models of Tuberculosis
22: Rabbit Model of Mycobacterial Diseases
23: Laboratory Models of Tuberculosis: Guinea Pigs
24: Of Mice and Mycobacteria: Lessons from a Manipulatable Model
25: Non-human Primate Laboratory Models of Tuberculosis
Part VI: Other Mycobacterial Diseases
26: Mycobacterium leprae in Humans
27: Animal Models for Leprosy Research
28: Mycobacterium avium subsp. paratuberculosis Infection, Immunology and Pathology of Livestock
