Mesenchymal Stem Cell in Veterinary Sciences

Mesenchymal Stem Cell in Veterinary Sciences PDF book focuses on mesenchymal stem cells (MSCs) of animal origin, including their isolation, characterization, and clinical applications.

After briefly discussing the historical development of the field of stem cell research, it describes the basic properties and nature of stem cells particularly in relation to MSCs. In turn, it reviews materials and methods used to isolate MSCs from various sources, culture expansion, characterization and long-term storage. It also explores the therapeutic efficacy, immunomodulation and anti-inflammatory, and differentiation properties of MSCs.

Importantly, the book discusses the applications of genetic engineering to enhance the efficacy and potential of MSCs in regenerative medicine. The book largely addresses the potential applications of mesenchymal stem cells in therapies for important species of domesticated animals including sheep, goats, cattle, buffalo, cats, dogs and horses. Finally, the book presents an abridgement of challenges and future prospects of stem cell research and application in medicine, in general and veterinary sciences, in particular.

  • Reviews basic properties and clinical applications of mesenchymal stem cells in regenerative medicine
  • Summarizes methods for isolation, characterisation, and cryopreservation of MSCs
  • Discusses the immunomodulation and anti-inflammatory properties of MSCs
  • Describes the role of genetic engineering in enhancing the therapeutic capabilities of MSCs
Table of Contents

1 Introduction to Stem Cells  1
M. B. Gugjoo
2 Mesenchymal Stem Cell and Its Properties  13
M. B. Gugjoo, Amar Pal, and G. T. Sharma
3 Mesenchymal Stem Cell Isolation, Culture, Characterization
and Cryopreservation  27
M. B. Gugjoo, Amar Pal, V. Chandra, and G. T. Sharma
4 Mesenchymal Stem Cell Immuno-Modulatory
and/Anti-Inflammatory Properties  47
M. B. Gugjoo and Amar Pal
5 Mesenchymal Stem Cell Differentiation Properties and Available
Microenvironment  67
M. B. Gugjoo and Amar Pal
6 Mesenchymal Stem Cell Genetic Engineering and Regenerative
Medicine  89
M. B. Gugjoo, E. Rasool, and Amar Pal
7 Sheep Mesenchymal Stem Cell Basic Research and Potential
Applications  99
M. B. Gugjoo and Amar Pal
8 Goat Mesenchymal Stem Cell Basic Research and Potential
Applications  153
M. B. Gugjoo, Amar Pal, M. R. Fazili, R. A. Shah, M. S. Mir, and
G. T. Sharma
9 Cattle/Buffalo Mesenchymal Stem Cell Basic Research and
Potential Applications  181
M. B. Gugjoo, Amar Pal, M. R. Fazili, R. A. Shah, and G. T. Sharma
10 Cat Mesenchymal Stem Cell Characteristics and
Potential Applications  197
M. B. Gugjoo and Amar Pal

11 Dog Mesenchymal Stem Cell Basic Research and
Potential Applications  213
M. B. Gugjoo, Amar Pal, and G. T. Sharma
12 Equine Mesenchymal Stem Cell Basic Research and Potential
Applications  283
M. B. Gugjoo, Amar Pal, D. M. Makhdoomi, and G. T. Sharma
13 Future of Mesenchymal Stem Cell Research  333
M. B. Gugjoo and Amar Pal

File Size3 MB
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