Knobil and Neill’s Physiology of Reproduction, 4th Edition (Two-Volume Set)

The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context.

  • The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field.
  • Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction.
  • Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.
Table of Contents

Volume 1
Section 1: Gametes, Fertilization and Embryogenesis
1. Meiosis
2. Ooycte
3. Sperm
4. Fertilization
5. Gamete and Zygote Transport
6. Pre-implantation Embryo Development
7. Sex Determination and Differentiation

 

Section 2: Gonadal Steroids, Pituitary and Hypothalamus
8. Human Steroid Biosynthesis
9. Gonadal Steroid Action
10. Physiology of the Gonadotroph
11. GnRH neuronal network
12. Hypothalamic Control of Prolactin Secretion
13. CNS Control of Oxytocin Release

Section 3: Male Reproductive System
14. Testicular Development
15. Spermatogonial Stem Cells
16. Hormone Signaling in the Testis
17. Epididymis
18. Accessory Male Sex Structures
19. Immunophysiology of Male Reproductive Tract

Section 4: Female Reproductive System
20. Gonadotropin Signaling in the Ovary
21. Follicular Development: Mouse, Sheep and Human Models
22. Ovulation and Luteinization
23. Structure, Function and Regulation of the Corpus Luteum
24. The Oviduct and Endometrium
25. Steroid Receptors in the Ovary and Uterus

Volume 2
Section 5: Physiological Control Systems and Governing Gonadal Function
26. Control of the Ovarian Cycle of the Rat
27. Control of the Ovarian Cycle of the Sheep
28. Control of the menstrual cycle
29. Pathophysiology of the menstrual cycle
30. Puberty in the Rat
31. Puberty in Sheep
32. Puberty in Non-human Primates and Humans
33. Comparative Aspects of Reproduction
34. Seasonal Regulation of Reproduction in Mammals
35. Appetite, Metabolism and Reproduction
36. Stress and Reproductive System
37. Aging of the Hypothalamo-Pituitary-Gonadal Axis

Section 6: Pregnancy and Lactation
38. Implantation
39. Placenta and Placental Transport Function
40. Placental Endocrine Function and Hormone Action
41. Immunology of Pregnancy
42. Parturition
43. Maternal Physiological Adaptation to Pregnancy
44. Maternal Brain Adaptation to Pregnancy
45. Fetal Epigenetic Origins of Disease
46. Lactation and its Hormonal Control

Section 7: Reproductive Behavior and Its Control
47. Sexual Differentiation of the Brain
48. Mate Selection and Pair Bonding
49. Male Sexual Behavior
50. Female Sexual Behavior
51. Parental Behavior
52. Epigenetic Control of Reproduction

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