Giardia and Cryptosporidium: From Molecules to Disease

Giardia and Cryptosporidium: From Molecules to Disease

By Guadalupe Ortega-Pierres, Simone M. Cacciò, Ronald Fayer, Theo G. Mank, Huw V. Smith and R.C. Andrew Thompson

Giardia and Cryptosporidium: From Molecules to Disease PDF. Giardia and Cryptosporidium are both parasites of considerable global interest due to the gastrointestinal problems the organisms can cause in humans as well as domestic and wild animals. This book presents an overview of recent research. The chapters discuss topics from taxonomy; nomenclature and evolution to molecular epidemiology; advances in diagnostics; and zoonotic, and human and animal health issues. The book serves as a reference for researchers and students in parasitology.

Table of Contents
The impact of Giardia on science and society.

Cryptosporidium in cattle: from observing to understanding.

Names do matter.

Centenary of the genus Cryptosporidium: from morphological to molecular species identification.

Molecular epidemiology of human cryptosporidiosis in developing countries.

Molecular epidemiology and typing of non-human isolates of Cryptosporidium.

Insights into the molecular detection of Giardia duodenalis: implications for epidemiology.

Wildlife with Giardia: villain, or victim and vector?

The role of livestock in the foodborne transmission of Giardia duodenalis and Cryptosporidium spp. to humans.

The risk of zoonotic genotypes of Cryptosporidium spp. in watersheds.

Clinical presentation in Cryptosporidium-infected patients.

Molecular epidemiology of Cryptosporidium and Giardia infections.

Advances in diagnosis: is microscopy still the benchmark?

Control of Cryptosporidium and Giardia in surface water by disinfection.

Towards methods for detecting UV-induced damage in individual Cryptosporidium parvum and Cryptosporidium hominis oocysts by immunofluorescence microscopy.

Effect of environmental and conventional water treatment processes on waterborne Cryptosporidium oocysts.

Methods for genotyping and subgenotyping Cryptosporidium spp. oocysts isolated during water and food monitoring.

Intervention in waterborne disease.

Occurrence and control of Naegleria fowleri in drinking water wells.

Environmental factors influencing the survival of Cyclospora cayetanensis.

Recent advances in the developmental biology and life cycle of Cryptosporidium.

Basic biology of Giardia lamblia: further studies on median body and funis.

Giardia intestinalis: a microaerophilic parasite with mitochondrial ancestry.

Cytoskeleton-based lipid transport in a parasitic protozoan, Giardia lamblia.

Signalling during Giardia differentiation.

Preliminary analysis of the Cryptosporidium muris genome.

Proteomic analyses in Giardia.

Proteomic and genomic approaches to understanding the ‘power plant’ of Cryptosporidium.

Energy metabolism and carbon flow in Cryptosporidium parvum.

The surface protein repertoires of Cryptosporidium spp. and other apicomplexans.

Giardan: structure, synthesis, regulation and inhibition.

Protein kinase C in Giardia duodenalis: a family affair.

Secretory granule biogenesis and the organization of membrane compartments via SNARE proteins in Giardia lamblia.

Molecular mechanisms of Cryptosporidium-induced host actin cytoskeleton dynamics.

Pathogenic mechanisms in giardiasis and cryptosporidiosis.

Interferon-gamma (IFN-γ) in immunological control of cryptosporidial infection.

Immune response to Giardia infection: lessons from animal models.

Drug treatment and novel drug targets against Giardia and Cryptosporidium.

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