
By Curtis D. Klaassen
Casarett & Doull’s Toxicology: The Basic Science of Poisons 9th Edition equips you with an unsurpassed understanding of modern toxicology, including the key principles, concepts, mechanisms, chemical-specific toxicity, and modes of thought that are the foundation of the discipline.
This trusted classic not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic responses of toxic substance available anywhere.
Many new contributors capture the progress made in toxicology over the past few years:
This edition is markedly updated from the previous edition, with more than one-third of the chapters authored by scientists who have not made previous contributions to the book.

Table of Contents
- Unit I: General Principles of Toxicology
- The Evolving Journey of Toxicology: A Historical Glimpse
- Principles of Toxicology
- Mechanisms of Toxicity
- Risk Assessment
- Unit II: Disposition of Toxicants
- Absorption, Distribution, and Excretion of Toxicants
- Biotransformation of Xenobiotics
- Toxicokinetics
- Unit III: Non-Organ-Directed Toxicity
- Chemical Carcinogenesis
- Genetic Toxicology
- Developmental Toxicology
- Unit IV: Target Organ Toxicity
- Toxic Responses of the Blood
- Toxic Responses of the Immune System
- Toxic Responses of the Liver
- Toxic Responses of the Kidney
- Toxic Responses of the Respiratory System
- Toxic Responses of the Nervous System
- Toxic Responses of the Cornea, Retina, and Central Visual System
- Toxic Responses of the Heart and Vascular System
- Toxic Responses of the Skin
- Toxic Responses of the Endocrine System
- Toxic Responses of the Reproductive System
- Unit V: Toxic Agents
- Toxic Effects of Pesticides
- Toxic Effects of Metals
- Toxic Effects of Solvents and Vapors
- Toxic Effects of Radiation and Radioactive Materials
- Toxic Effects of Plants and Animals
- Food Toxicology: Fundamental and Regulatory Aspects
- Toxic Effects of Calories
- Nanoparticle Toxicology
- Unit VI: Environmental Toxicology
- Ecotoxicology
- Air Pollution
- Unit VII: Applications of Toxicology
- Analytical and Forensic Toxicology
- Clinical Toxicology
- Occupational Toxicology
- Regulatory Toxicology
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