Promethazine

Promethazine In Dogs & Cats: Uses, Dosage and Side Effects

Overview

• Binds to H1 histamine receptors and prevents histamine from binding.

Uses of Promethazine

• Management of allergic disease.
• Early treatment of anaphylaxis.

Dose of Promethazine in Dogs and Cats

Dogs, Cats:

• 0.2–0.4 mg/kg i.v., i.m. q6–8h, 12.5–25 mg/dog p.o. q24h.

Side Effects of Promethazine in Dogs and Cats

• May cause mild sedation.
• May reduce the seizure threshold.

Contraindications of Promethazine in Dogs and Cats

• No information is available.

Some Notes:

• Specific doses for dogs and cats have not been determined by pharmacokinetic studies. Not widely used.
• Use with caution in cases with urinary retention, angle-closure glaucoma and pyloroduodenal obstruction.