Chlorphenamine

Chlorphenamine: Uses, Dosage and Side Effects

Overview

Binds to H1 histamine receptors to prevent histamine binding.

Uses of Chlorphenamine

1. Management of allergic disease.
2. Prevention and early treatment of anaphylaxis.
3. Used as premedication before transfusions and certain chemotherapeutic agents.
4. Use with caution in cases with urinary retention, angle-closure glaucoma and pyloroduodenal obstruction.

Dose of Chlorphenamine in Dogs and Cats

Dogs:

Antihistamine: 4–8 mg/dog p.o. q8h; 2.5–10 mg/dog i.m. or slow i.v.

Cats:

Antihistamine: 2–4 mg/cat p.o. q8–12h; 2–5 mg/cat i.m. or slow i.v.

Side Effects of Chlorphenamine in Dogs and Cats

• May cause mild sedation.
• May reduce the seizure threshold.

Contraindications of Chlorphenamine in Dogs and Cats

No information is available.