Pancreatic Enzyme Supplements

Pancreatic Enzyme Supplements In Dogs & Cats: Uses, Dosage and Side Effects

Overview

• Exogenous replacement enzymes.

Uses of Pancreatic enzyme supplements

• Pancreatic enzymes, including lipase, protease, and amylase, are utilized to manage symptoms of exocrine pancreatic insufficiency (EPI).
• Fresh raw or fresh-frozen pig pancreas, at a dosage of approximately 100 g per meal, can serve as an effective treatment for EPI. However, its use is constrained by limited availability and the potential risk of pathogen ingestion.
• Non-enteric-coated powders, as well as enteric-coated granules and tablets, are accessible for EPI treatment.
• Vitamin B12 therapy may enhance efficacy, especially in cases of associated hypocobalaminaemia.
• The simultaneous use of acid blockers is not deemed cost-effective, and there is no necessity for pre-incubation with food. Dosing should be followed by food or water

Dose of Pancreatic Enzyme Supplements in Dogs and Cats

Dogs, Cats:

• Use the manufacturer’s recommendations to determine the minimum required initially.
• The dose should be adjusted to obtain faeces of normal consistency and will thus be variable.
• When signs are controlled, it is advisable to reduce the dose gradually over a 7-day
  period to determine the minimally effective dose.
• Lypex capsules must be opened and the contents sprinkled in with food for every meal.

Side Effects of Pancreatic Enzyme Supplements in Dogs and Cats

• Powdered non-coated enzyme formulations can sporadically lead to contact dermatitis of the lips, and some dogs may exhibit an offensive odour.
• The use of non-coated pancreatic enzymes may result in the development of oral or oesophagal ulcers, emphasizing the importance of administering doses with food or water.
• Elevated doses of non-coated pancreatic enzymes have the potential to induce diarrhoea and symptoms of gastrointestinal cramping.

Contraindications of Pancreatic Enzyme Supplements in Dogs and Cats

• No information is available.

Some Notes:

• The effectiveness may be diminished by antacids (magnesium hydroxide, calcium carbonate).