Glucagon

Glucagon In Dogs and Cats: Uses, Dosage and Side Effects

Overview

• Binds to a specific receptor and counteracts most of the effects of insulin.

Uses of Glucagon

• Insulin overdose.
• Use only when feeding and glucose administration has failed to maintain a response.
• Duration of activity is unknown in dogs but likely to be 1–2 hours.
• When using glucagon, blood glucose levels should be monitored hourly.

Dose of Glucagon in Dogs and Cats

Dogs, Cats:

• Hypoglycaemia: 50 ng (nanograms)/kg i.v., i.m. once followed by infusion of 10–15 ng/kg/min i.v., i.m.; may increase up to 40 ng/kg/min i.v., i.m., depending on blood glucose measurements.

Side Effects of Glucagon in Dogs and Cats

• Vomiting is the main adverse reaction reported in humans.
• Anaphylaxis may occur but is rare.
• Experience with dogs is too limited to provide clear guidance.

Contraindications of Glucagon in Dogs and Cats

• Normoglycaemia.