Preface vi

Acknowledgements vi

Abbreviations and definitions vii

About the companion website viii

Section I Introductory Bacteriology

1. Structure of bacterial cells 2

2. Cultivation, preservation and inactivation of bacteria 4

3. Bacterial genetics and genetic variation 6

4. Molecular diagnostic methods 10

5. Laboratory diagnosis of bacterial disease 12

6. Molecular subtyping of bacteria 14

7. Antibacterial agents 18

8. Antimicrobial susceptibility testing 20

9. Bacterial resistance to antimicrobial drugs 22

10. Bacterial infections 24

11. Structure and components of the immune system 26

12. Adaptive immunity 30

13. Protective immune responses against infectious agents 32

Section II Pathogenic Bacteria

14. Staphylococcus species 36

15. Streptococci 38

16. Corynebacterium species and Rhodococcus equi 40

17. Actinobacteria 42

18. Listeria species 46

19. Erysipelothrix rhusiopathiae 47

20. Bacillus species 48

21. Clostridium species 50

22. Mycobacterium species 54

23. Enterobacteriaceae 58

24. Pseudomonas aeruginosa 62

25. Burkholderia mallei and Burkholderia pseudomallei 63

26. Actinobacillus species 64

27. Pasteurella species, Mannheimia haemolytica and Bibersteinia trehalosi 66

28. Histophilus, Haemophilus and Avibacterium species 68

29. Taylorella equigenitalis 70

30. Moraxella bovis 71

31. Francisella tularensis 72

32. Lawsonia intracellularis 73

33. Bordetella species 74

34. Brucella species 76

35. Campylobacter species 80

36. Spirochaetes 82

37. Pathogenic, anaerobic, non-spore-forming Gram-negative bacteria 86

38. Mycoplasmas 88

39. Chlamydiae 92

40. Rickettsiales and Coxiella burnetii 94

Section III Mycology

41. General features of fungi associated with disease in animals 98

42. Dermatophytes 100

43. Aspergillus species 102

44. Yeasts and disease production 104

45. Dimorphic fungi 106

46. Zygomycetes of veterinary importance 108

47. Mycotoxins and mycotoxicoses 110

48. Pathogenic algae and cyanobacteria 114

49. Antifungal chemotherapy 116

Section IV Viruses and Prions

50. Nature, structure and taxonomy of viruses 120

51. Replication of viruses 122

52. Laboratory diagnosis of viral disease 126

53. Antiviral chemotherapy 128

54. Herpesviridae 132

55. Papillomaviridae 136

56. Adenoviridae 138

57. Poxviridae 140

58. Asfarviridae 142

59. Bornaviridae 143

60. Parvoviridae 144

61. Circoviridae 146

62. Astroviridae 147

63. Retroviridae 148

64. Reoviridae 152

65. Orthomyxoviridae 154

66. Paramyxoviridae 156

67. Rhabdoviridae 160

68. Bunyaviridae 162

69. Birnaviridae 163

70. Picornaviridae 164

71. Caliciviridae 166

72. Coronaviridae 168

73. Arteriviridae 170

74. Togaviridae 171

75. Flaviviridae 172

76. Prions 176

Section V Prevention and Control of Infectious Disease

77. Biosecurity 180

78. Vaccination 184

79. Disinfection 188

Appendix: relevant websites 190

Index 191