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Immunity to Parasitic Infection

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Immunity To Parasitic Infection Book Cover

By Tracey Lamb

Immunity to Parasitic Infection is an in-depth scientific reference that explores how the immune system responds to parasitic infections and how parasites interact with host immunity. The book provides a structured overview of immunoparasitology, combining fundamental immunology with detailed analysis of protozoan and helminth infections affecting humans.

Beginning with a clear introduction to the immune system, the text guides readers through innate and adaptive immune responses before examining specific parasite groups, including protozoa such as Plasmodium, Toxoplasma, Giardia, Leishmania, and Trypanosomes, as well as major helminth infections. Each chapter focuses on host–parasite interactions, immune evasion strategies, immunopathology, and memory responses.

The book also addresses the growing importance of co-infections, highlighting how multiple parasitic diseases interact with each other and with conditions such as HIV. Later sections examine the role of parasites in immune regulation, the hygiene hypothesis, and emerging therapeutic approaches including parasite-based immunomodulation and vaccine development.

Immunity to Parasitic Infection serves as a valuable academic resource for researchers, postgraduate students, clinicians, and professionals in immunology, parasitology, infectious diseases, and tropical medicine who seek a clear and up-to-date understanding of immune responses to parasitic disease.

Table of Contents (Summarized)
  • Contributors
  • Introduction: Immunoparasitology & Modern Immunology
  • Section 1 – Fundamentals of Immunology
  • Immune system overview: innate & adaptive immunity
  • Complement system, MHC, T & B cells
  • Cell trafficking, effector mechanisms & hypersensitivity
  • Section 2 – Protozoan Infections
  • Protozoa classification & evolution
  • Apicomplexa: Malaria, Toxoplasma, Cryptosporidium
  • Giardia, Leishmania, Trypanosomes (African & Chagas)
  • Host immune responses, evasion & immunopathology
  • Section 3 – Helminth Infections
  • Helminth biology & parasitism evolution
  • Nematodes: Filaria, Ascaris, Hookworms, Trichuris, Trichinella
  • Trematodes: Schistosomes
  • Cestodes: Tapeworms & Echinococcosis
  • Section 4 – Co-Infection & Immune Interactions
  • Parasite–parasite interactions
  • HIV with Malaria, Leishmania & Schistosomes
  • GI nematodes and malaria co-infection models
  • Section 5 – Immunoregulation & Therapeutic Parasites
  • Hygiene hypothesis & early immune programming
  • Helminths in allergy & chronic inflammatory diseases
  • Nematodes as therapeutic organisms
  • Section 6 – Vaccines Against Parasitic Diseases
  • Vaccines for Malaria, Leishmaniasis & Hookworms
  • Filarial nematode vaccine strategies
  • Future directions in antiparasitic vaccination
  • Abbreviations
  • Glossary
  • Index

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File Size 31.4 MB
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