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HomeClinical SciencesOncologyElectroporation in Veterinary Oncology Practice: Electrochemotherapy and Gene Electrotransfer for Immunotherapy

Electroporation in Veterinary Oncology Practice: Electrochemotherapy and Gene Electrotransfer for Immunotherapy

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Electroporation In Veterinary Oncology Practice: Electrochemotherapy And Gene Electrotransfer For Immunotherapy Pdf Download

By Joseph A. Impellizeri

Electroporation in Veterinary Oncology Practice: Electrochemotherapy and Gene Electrotransfer for Immunotherapy is Written by an international team of experts, this book presents worldwide emerging therapy options for cancer treatments in veterinary oncology practice.

Electroporation offers a precision tool to target cancer cells without destroying surrounding tissue structures. The opening of tumor cell membranes facilitates local control of solid tumors either through the delivery of chemotherapeutics or by direct ablation of tissues using electric fields. In addition, transfer of gene-based products into the cancer cells can be used for genetic vaccination to achieve systemic responses and cancer control.

Readers will discover valuable reference texts for practitioner education, including chapters on electrodes for unique anatomical access and treatment planning for deep-seated tumors, different immunotherapy applications with gene electrotransfer, calcium electroporation, irreversible electroporation applications and combinations with other common treatments such as surgery, radiation therapy and chemotherapy.

Therapy options with electroporation are gaining interest around the world in both human and veterinary oncology, making Electroporation in Veterinary Oncology Practice: Electrochemotherapy and Gene Electrotransfer for Immunotherapy book valuable for oncologists, surgeons, primary care veterinarians, residents, interns and students at veterinary schools, where teaching of Electrochemotherapy will become part of the curriculum.

Table of Contents

Table of Contents:

Section A: Technology and Science of Electroporation: Fundamentals

1. Electroporation: Technology and Science

2. Electrodes and electric field distribution in clinical practice

Section B: Therapeutic Applications with Electroporation in Veterinary Oncology Practice

3. Electrochemotherapy in Veterinary Oncology

4. Treating Mast Cell Tumors with Electrochemotherapy

5. Electrochemotherapy for the treatment of transitional cell carcinoma in dogs

6. Calcium electroporation in veterinary medicine

7. Irreversible Electroporation Applications

8. Electrochemotherapy as a multi-modality component of cancer treatment- combinations with surgery, radiation therapy and chemotherapy

Section C: Gene-Electrotransfer and Immunotherapy Applications with Electroporation

9. Gene Electrotransfer

10. Immunotherapy Applications (Telomerase and HER2) with Gene Electrotransfer

11. Interleukin-12 gene electrotransfer in veterinary oncology

12. Canine Melanoma and Osteosarcoma Immunotherapy by means of in vivo DNA Electroporation

Section D: Evolution of the Field and New Applications with Electroporation-Based Treatments: Outlook

13. Electrodes for Unique Anatomical Access in Electroporation

14. New Electrodes and Treatment Planning for deep-seated and intraluminal localized tumors

15. Advancing Electroporation Systems

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