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HomeAnimals BooksAquatic AnimalsImmunobiology of the Shark

Immunobiology of the Shark

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Immunobiology Of The Shark Cover

By Sylvia L. Smith, Robert B. Sim and Martin F. Flajnik

Immunobiology of the Shark is a comprehensive scientific reference exploring the structure, evolution, and function of the immune system in sharks and other cartilaginous fishes. Research over the past decades has shown that sharks represent a powerful alternative animal model for understanding the origins and mechanisms of vertebrate immunity.

  • Provides in-depth coverage of cellular, genetic, and molecular immune processes, combining classical histological observations with modern genomic and immunogenetic approaches. Topics include innate and adaptive immunity, immunoglobulin diversity, MHC molecules, V(D)J recombination, cytokines, and antimicrobial compounds unique to elasmobranchs.
  • Highlights how shark immunology has contributed to modern immunological theory and biomedical research. High-quality illustrations and detailed references make it especially valuable for advanced study.
  • This book is well suited for immunologists, comparative biologists, evolutionary researchers, fish biologists, and scientists interested in non-mammalian immune models, as well as graduate students
Table of Contents

The Diversity and Natural History of Chondrichthyan Fishes.

Athena and the Evolution of Adaptive Immunity.

Shark Reproduction, Immune System Development and Maturation.

Sites of Immune Cell Production in Elasmobranch Fishes: Lymphomyeloid Tissues and Organs.

Elasmobranch Blood Cells.

Leukocyte Function in Elasmobranch Species: Phagocytosis, Chemotaxis, and Cytotoxicity. Cytokines of Cartilaginous Fish.

Shark Complement: Genes, Proteins and Function.

MHC Molecules of Cartilaginous Fishes.

Considering V(D)J Recombination in the Shark.

Shark Immunoglobulin Light Chains.

Shark T-Cell Receptors.

The Shark-Family (Cartilaginous Fish) Immunogenome.

In Vitro Culture of Elasmobranch Cells.

Antimicrobial Molecules of Sharks and Other Elasmobranchs: A Review.

Shark-Derived Immunomodulators.

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