Pentobarbital (Pentobarbitone)

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Pentobarbital (Pentobarbitone) In Dogs & Cats: Uses, Dosage and Side Effects

Pentobarbital (Pentobarbitone) In Dogs & Cats: Uses, Dosage and Side Effects

Overview

  • CNS depressant: direct action on the medulla results in rapid depression of the respiratory centre followed by cardiac arrest.

Uses of Pentobarbital (Pentobarbitone)

  • For euthanasia of cats and dogs.

Dose of Pentobarbital (Pentobarbitone) in Dogs and Cats

Dogs, Cats:

  • Euthanasia: 80 mg/kg in debilitated animals, up to 120–160 mg/kg in younger and fitter animals, rapid i.v. injection.

Drug Dosage Calculator

You Should Give:

Side Effects of Pentobarbital (Pentobarbitone) in Dogs and Cats

  • Narcotic excitement may be seen in agitated animals.
  • Agonal gasping is sometimes seen.

Contraindications of Pentobarbital (Pentobarbitone) in Dogs and Cats

  • Should not be given i.m. as it is painful and slow to act.
  • Do not use solutions intended for euthanasia to try to control seizures.

Some Notes:

  • Antihistamines and opioids increase the effect of pentobarbital.
  • Strain animals to prevent narcotic excitement.
  • Prefer intravenous (i.v.) administration for euthanasia drugs.
  • Consider intraperitoneal if i.v. is challenging.
  • The intrathoracic route is a last resort due to lung injection risks.
  • Direct heart chamber injection is rapid but challenging.
  • Pentobarbital is mentioned, but no authorized UK product for seizures.
  • Emphasizes selecting suitable products for humane euthanasia.
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