I. Foundations
1. Evolution, Science, and Molecular Biology
2. DNA: The Repository of Biological Information
3. Chemical Basis of Information Molecules
4. Protein Structure
5. Protein Function
II. Nucleic Acid Structure and Methods
6. DNA and RNA Structure
7. Studying Genes
8. Genomes, Transcriptomes, and Proteomes
9. Topology: Functional Deformations of DNA
10. Nucleosomes, Chromatin, and Chromosome Structure
III. Information Transfer
11. DNA Replication
12. DNA Mutation and Repair
13. Recombinational DNA Repair and Homologous Recombination
14. Site-Specific Recombination and Transposition
15. Transcription: DNA-Dependent Synthesis of RNA
16. RNA Processing
17. The Genetic Code
18. Protein Synthesis
IV. Regulation
19. Regulating the Flow of Information
20. The Regulation of Gene Expression in Bacteria
21. The Transcriptional Regulation of Gene Expression in Eukaryotes
22. The Posttranscriptional Regulation of Gene Expression in Eukaryotes
Appendix: Model Organisms
Glossary
Solutions to Problems
Index
