Knobil and Neill’s Physiology of Reproduction, 4th Edition is a definitive reference textbook covering human and comparative reproductive physiology. Widely used in graduate teaching and research, this two-volume set provides historical context alongside modern advances in reproductive biology.
The fourth edition reflects major developments in stem cell research, signaling pathways, inflammation, and the integration of new animal models. Content is presented at molecular, cellular, and organismal levels, offering a comprehensive and comparative understanding of reproductive physiology for researchers, clinicians, and advanced students.
The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field.
Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction.
Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.
Table of Contents
Knobil and Neill’s Physiology of Reproduction – PDF Contents
Volume 1
Section 1: Gametes, Fertilization and Embryogenesis
1. Meiosis
2. Ooycte
3. Sperm
4. Fertilization
5. Gamete and Zygote Transport
6. Pre-implantation Embryo Development
7. Sex Determination and Differentiation
Section 2: Gonadal Steroids, Pituitary and Hypothalamus
8. Human Steroid Biosynthesis
9. Gonadal Steroid Action
10. Physiology of the Gonadotroph
11. GnRH neuronal network
12. Hypothalamic Control of Prolactin Secretion
13. CNS Control of Oxytocin Release
Section 3: Male Reproductive System
14. Testicular Development
15. Spermatogonial Stem Cells
16. Hormone Signaling in the Testis
17. Epididymis
18. Accessory Male Sex Structures
19. Immunophysiology of Male Reproductive Tract
Section 4: Female Reproductive System
20. Gonadotropin Signaling in the Ovary
21. Follicular Development: Mouse, Sheep and Human Models
22. Ovulation and Luteinization
23. Structure, Function and Regulation of the Corpus Luteum
24. The Oviduct and Endometrium
25. Steroid Receptors in the Ovary and Uterus
Volume 2
Section 5: Physiological Control Systems and Governing Gonadal Function
26. Control of the Ovarian Cycle of the Rat
27. Control of the Ovarian Cycle of the Sheep
28. Control of the menstrual cycle
29. Pathophysiology of the menstrual cycle
30. Puberty in the Rat
31. Puberty in Sheep
32. Puberty in Non-human Primates and Humans
33. Comparative Aspects of Reproduction
34. Seasonal Regulation of Reproduction in Mammals
35. Appetite, Metabolism and Reproduction
36. Stress and Reproductive System
37. Aging of the Hypothalamo-Pituitary-Gonadal Axis
Section 6: Pregnancy and Lactation
38. Implantation
39. Placenta and Placental Transport Function
40. Placental Endocrine Function and Hormone Action
41. Immunology of Pregnancy
42. Parturition
43. Maternal Physiological Adaptation to Pregnancy
44. Maternal Brain Adaptation to Pregnancy
45. Fetal Epigenetic Origins of Disease
46. Lactation and its Hormonal Control
Section 7: Reproductive Behavior and Its Control
47. Sexual Differentiation of the Brain
48. Mate Selection and Pair Bonding
49. Male Sexual Behavior
50. Female Sexual Behavior
51. Parental Behavior
52. Epigenetic Control of Reproduction
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