Antineoplastic

Lomustine (CCNU) In Dogs & Cats: Uses, Dosage and Side Effects Overview Interferes with the synthesis and function of DNA, RNA and proteins. Antitumour activity...

Hydroxycarbamide (Hydroxyurea): Uses, Dosage and Side Effects Overview It inhibits ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides (important precursors for DNA synthesis and repair). It...

Gemcitabine in Dogs and Cats: Uses, Dosage and Side Effects Overview Metabolites of the drug inhibit the enzyme ribonucleotide reductase and compete with endogenous nucleotides...

Fluorouracil (5-FU): Uses, Dosage and Side Effects Overview Fluorouracil's metabolites stop the production of pyrimidine, which blocks DNA from being synthesised and stops it from...

Finasteride: Uses, Dosage and Side Effects Overview Competitively inhibits dihydrotestosterone (DHT) production within the prostate. DHT is the main hormonal stimulus for the development of...

Epirubicin: Uses, Dosage and Side Effects Overview Epirubicin is a semisynthetic stereoisomer of doxorubicin. Intracellularly its metabolism results in the production of cytotoxic free radicals. ...

Doxorubicin (Adriamycin): Uses, Dosage and Side Effects Overview Inhibits DNA synthesis and function. Uses of Doxorubicin (Adriamycin) Treatment of lymphoma, soft tissue sarcomas, osteosarcoma and haemangiosarcoma. ...

Dactinomycin (Actinomycin-D): Uses, Dosage and Side Effects Overview DNA synthesis and function-inhibiting antibacterial antineoplastic. RNA and protein synthesis inhibition may also factor in the cytotoxic...

Dacarbazine: Uses, Dosage and Side Effects Overview Dacabazine methylates nucleic acids and prevents the synthesis of DNA, RNA, and proteins. Uses of Dacarbazine Management of melanoma,...

Cyclophosphamide: Uses, Dosage and Side Effects Overview Cross-linking of DNA by metabolic byproducts inhibits both DNA synthesis and its activity. Uses of Cyclophosphamide Treatment of lymphoproliferative and...