
By Bradford P. Smith
Large Animal Internal Medicine 5th Edition presents a problem-based approach to the diagnosis and management of diseases in horses, cattle, sheep, and goats. Organized around clinical signs and laboratory findings, it guides practitioners from presenting complaint to diagnosis and treatment.
The text includes updated information on vaccines and vaccination protocols, DNA and PCR diagnostics, colostrum supplements, and advances in laboratory testing. Coverage spans more than 150 clinical manifestations, supported by extensive diagnostic interpretation and current therapeutic strategies.
The Large Animal Internal Medicine 5th Edition PDF remains a comprehensive reference for veterinarians and students seeking authoritative guidance in large animal clinical medicine.

Table of Contents
- Part I: History, Physical Examination, And Medical Records
- Chapter 1: Ruminant Examination And Records
- Chapter 2: Equine Examination And Records
- Part II: Manifestations Of Disease
- Chapter 3: Pain
- Chapter 4: Body Temperature Disorders
- Chapter 5: Respiratory Disorders
- Chapter 6: Cardiovascular And Hemolymphatic Disorders
- Chapter 7: Alimentary And Hepatic Disorders
- Chapter 8: Neurologic Disorders
- Chapter 9: Body Weight Alterations
- Chapter 10: Urinary Disorders
- Chapter 11: Skin Disorders
- Chapter 12: Sexual Function Disorders
- Chapter 13: Musculoskeletal Disorders
- Chapter 14: Collapse And Sudden Death
- Part III: Neonatal Disorders And Management
- Chapter 15: The Peripartum Mare
- Chapter 16: Newborn Foal Assessment
- Chapter 17: Neonatal Foal Diseases
- Chapter 18: The Peripartum Ruminant
- Chapter 19: Neonatal Ruminant Examination
- Chapter 20: Neonatal Ruminant Diseases
- Chapter 21: Colostrum And Milk Replacers
- Part IV: Laboratory Tests And Diagnostics
- Chapter 22: Clinical Chemistry
- Chapter 23: Cytology And Hematology
- Chapter 24: Erythron Disorders
- Chapter 25: Leukogram Disorders
- Chapter 26: Blood Protein Disorders
- Chapter 27: Hemostasis Disorders
- Chapter 28: Bone Marrow Analysis
- Chapter 29: Molecular Diagnostics
- Part V: Organ System Diseases
- Chapter 30: Cardiovascular Diseases
- Chapter 31: Respiratory Diseases
- Chapter 32: Alimentary Diseases
- Chapter 33: Hepatobiliary Diseases
- Chapter 34: Renal Diseases
- Chapter 35: Nervous System Diseases
- Chapter 36: Mammary Gland Disorders
- Chapter 37: Hematopoietic Diseases
- Chapter 38: Musculoskeletal Diseases
- Chapter 39: Eye Diseases
- Chapter 40: Skin Diseases
- Chapter 41: Endocrine And Metabolic Diseases
- Chapter 42: Muscle Diseases
- Chapter 43: Reproductive Diseases
- Part VI: Prevention And Therapy
- Chapter 44: Critical Care And Fluid Therapy
- Chapter 45: Antimicrobial Therapy
- Chapter 46: Biosecurity And Infection Control
- Chapter 47: Foreign Animal Diseases
- Chapter 48: Use Of Biologics
- Chapter 49: Parasite Control
- Chapter 50: Nutrition Of The Sick Animal
- Part VII: Genetic, Immunologic, And Toxic Disorders
- Chapter 51: Genetic Disorders
- Chapter 52: Genetic Testing
- Chapter 53: Immunologic Disorders
- Chapter 54: Toxic Disorders