{"id":779,"date":"2023-04-29T15:07:38","date_gmt":"2023-04-29T15:07:38","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=779"},"modified":"2023-04-29T15:09:03","modified_gmt":"2023-04-29T15:09:03","slug":"dantrolene","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/dantrolene\/","title":{"rendered":"Dantrolene"},"content":{"rendered":"

Dantrolene: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Dantrolene:$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Prevents the release of calcium ions from the sarcoplasmic reticulum in striated muscle, separating the excitation-contraction process.<\/li>\n
Vascular smooth muscle and cardiac muscle are typically unaffected because they do not mainly depend on calcium release for contraction.<\/li>\n<\/ul>\n
Uses of Dantrolene<\/strong><\/h2>\n
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Treatment of muscular spasms, including tetanus and urethral muscle spasm.<\/li>\n
The oral or intravenous therapy of malignant hyperthermia.<\/li>\n<\/ul>\n
N.B: <\/strong><\/p>\n
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Each vial should be reconstituted with 60 ml of water.<\/li>\n
The solution must be transparent and free of any observable particles prior to administration.<\/li>\n
Use the made solution within six hours and shield it from light.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Dantrolene in Dogs and Cats<\/strong><\/h2>\n
Dogs, Cats:<\/strong>
\n\u2022 Malignant hyperthermia: 2\u20135 mg\/kg i.v.
\n\u2022 Other indications: 0.5\u20132 mg\/kg p.o. q12h.<\/p>\n
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