{"id":606,"date":"2023-02-24T16:07:17","date_gmt":"2023-02-24T14:07:17","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=606"},"modified":"2023-04-29T14:51:36","modified_gmt":"2023-04-29T14:51:36","slug":"cimicoxib","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/cimicoxib\/","title":{"rendered":"Cimicoxib"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Cimicoxib: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-706 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/02\/Cimicoxib.jpg\" alt=\"Cimicoxib: Uses, Dosage and Side Effects\" width=\"629\" height=\"378\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<p>Cimicoxib limits the production of prostaglandins implicated in inflammation by selectively inhibiting COX-2.<\/p>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Cimicoxib<\/strong><\/h2>\n<ul>\n<li>Management of perioperative pain brought on by orthopedic or soft tissue surgery in dogs<\/li>\n<li>Treatment of pain and inflammation associated with osteoarthritis.<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Cimicoxib in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<p>2 mg\/kg p.o. q24h administered with or without food.<\/p>\n<p><strong>Cats:<\/strong><\/p>\n<p>Not authorized for cats.<\/p>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Cimicoxib in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Mild GI signs are commonly reported but most recover without treatment.<\/li>\n<li>Stop therapy if signs persist beyond 1\u20132 days or GI bleeding is suspected.<\/li>\n<li>A 3\u20135 day wash-out period should be allowed before starting therapy with another NSAID.<\/li>\n<li>There is a small risk that NSAIDs may precipitate cardiac failure in humans and this risk in animals is unknown.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Cimicoxib in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Not given to puppies younger than 10 weeks old.<\/li>\n<li>Don&#8217;t give to patients who are dehydrated, hypovolemic, hypotensive, have GI disorders, or have issues with blood coagulation.<\/li>\n<li>If cimicoxib is given to individuals with concurrent renal or hepatic impairment, there may be an increased risk involved, so close patient monitoring is necessary.<\/li>\n<li>Do not give to pregnant or lactating bitches.<\/li>\n<li>Do not administer glucocorticoids and other NSAIDs simultaneously or within 24 hours of each other.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>It is recommended to take one dose two hours prior to surgery, followed by three to seven days of treatment.<\/li>\n<li>Preoperatively, all NSAIDs should be provided with caution.<\/li>\n<li>Cimicoxib predominantly suppresses COX-2, however, it can still have a negative impact on renal perfusion when blood pressure is low.<\/li>\n<li>If hypotension during anesthesia is predicted, wait to administer cimicoxib until the animal is fully recovered and has returned to normal blood pressure.<\/li>\n<li>Cimicoxib&#8217;s metabolism will be slowed down by liver disease, increasing the risk of drug accumulation and overdose with repeated doses.<\/li>\n<li>An initial treatment term of six months is recommended for the reduction of pain and inflammation caused by osteoarthritis; this can be extended based on the clinical requirement for analgesic medication.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Cimicoxib: Uses, Dosage and Side Effects Overview Cimicoxib limits the production of prostaglandins implicated in inflammation by selectively inhibiting COX-2. Uses of Cimicoxib Management of perioperative pain brought on by orthopedic or soft tissue surgery in dogs Treatment of pain and inflammation associated with osteoarthritis. Dose of Cimicoxib in Dogs and Cats Dogs: 2 mg\/kg [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1226,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[],"class_list":["post-606","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anti-inflammatory-drugs"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/606","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=606"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/606\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1226"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=606"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=606"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=606"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}