{"id":339,"date":"2023-02-02T14:08:41","date_gmt":"2023-02-02T12:08:41","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=339"},"modified":"2023-04-21T20:55:43","modified_gmt":"2023-04-21T20:55:43","slug":"buprenorphine","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/buprenorphine\/","title":{"rendered":"Buprenorphine"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Buprenorphine: Uses, Dosage and Side Effects<\/strong><\/p>\n<h3><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-458 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/02\/Buprenorphine.jpg\" alt=\"Buprenorphine: Uses, Dosage and Side Effects\" width=\"635\" height=\"381\" \/><\/h3>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<p>It provides <strong>analgesia<\/strong> through high affinity, low intrinsic activity and slow dissociation with the mu receptor.<\/p>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Buprenorphine <\/strong><\/h2>\n<ul>\n<li>Relief of mild to moderate perioperative pain.<\/li>\n<li>It may antagonize the effects of full opioid agonists (e.g. methadone, fentanyl).<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Buprenorphine in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<ul>\n<li>Analgesia: 0.02 mg\/kg i.v., i.m., s.c. q6h.<\/li>\n<\/ul>\n<p><strong>Cats:<\/strong><\/p>\n<ul>\n<li>Analgesia: 0.02\u20130.03 mg\/kg i.v., i.m., s.c. q6h.<\/li>\n<\/ul>\n<p>Also well tolerated and effective when given <strong>orally transmucosal. <\/strong><br \/>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Buprenorphine in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Buprenorphine <strong>crosses the placenta<\/strong> and may exert sedative effects in neonates born to bitches and queens treated prior to parturition.<\/li>\n<li><strong>Pain on i.m. injection<\/strong> of the multidose preparation has been anecdotally reported.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Buprenorphine in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Do not use for premedication when the administration of potent opioids during surgery is anticipated.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Buprenorphine may be<strong> mixed with acepromazine<\/strong> or dexmedetomidine to provide sedation for minor procedures or pre-anesthetic medication.<\/li>\n<li>The <strong>onset of action<\/strong> of buprenorphine may be slower than methadone (&gt;15 min).<\/li>\n<li>The <strong>duration of effect<\/strong> is approximately 6 hours in cats and is likely to be similar in dogs.<\/li>\n<li>Buprenorphine is <strong>metabolized in the liver<\/strong>; some prolongation of effect may be seen with impaired liver function.<\/li>\n<li>The multidose preparation is<strong> unpalatable given sublingually<\/strong> due to the preservative.<\/li>\n<li>There is emerging evidence that the analgesic efficacy of buprenorphine <strong>s.c. may be less than similar doses of buprenorphine administered i.m. or i.v.<\/strong> to cats, therefore, this route is not recommended in cats or dogs<\/li>\n<li>In common with other <strong>opioids<\/strong>, buprenorphine will reduce the doses of other drugs required for induction and maintenance of anesthesia.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Buprenorphine: Uses, Dosage and Side Effects Overview It provides analgesia through high affinity, low intrinsic activity and slow dissociation with the mu receptor. Uses of Buprenorphine Relief of mild to moderate perioperative pain. It may antagonize the effects of full opioid agonists (e.g. methadone, fentanyl). Dose of Buprenorphine in Dogs and Cats Dogs: Analgesia: 0.02 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1120,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16,4],"tags":[],"class_list":["post-339","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-analgesics","category-anesthesia"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/339","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=339"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/339\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1120"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=339"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=339"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=339"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}