{"id":306,"date":"2023-02-01T12:58:07","date_gmt":"2023-02-01T10:58:07","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=306"},"modified":"2023-04-21T19:57:53","modified_gmt":"2023-04-21T19:57:53","slug":"azithromycin","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/azithromycin\/","title":{"rendered":"Azithromycin"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Azithromycin: Uses, Dosage and Side Effects<\/strong><\/p>\n<h3><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-432 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/02\/Azithromycin.jpg\" alt=\"Azithromycin: Uses, Dosage and Side Effects\" width=\"800\" height=\"480\" \/><\/h3>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>Time-dependent <strong>macrolide<\/strong> that binds to the 50S bacterial ribosome (like erythromycin), inhibiting peptide bond formation.<\/li>\n<li>Azithromycin has a<strong> longer tissue half-life than erythromycin<\/strong>, shows better oral absorption and is better tolerated in humans.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Azithromycin <\/strong><\/h2>\n<ul>\n<li><strong>Alternative to penicillin in allergic individuals<\/strong> as it has a similar, although not identical, antibacterial spectrum.<\/li>\n<li>Useful in the management of the <strong>respiratory tract.<\/strong><\/li>\n<li>Mild to moderate <strong>skin and soft tissue, and non-tubercular mycobacterial infections<\/strong>.<\/li>\n<li>Is used to treat<strong> chlamydophilosis<\/strong> in birds, but it has not proved possible to eliminate Chlamydia felis from chronically infected cats using azithromycin, even with once daily administration.<\/li>\n<li>Also reported for the treatment of<strong> Babesia gibsoni and Cytauxzoon felis.<\/strong><\/li>\n<li>In addition to its antimicrobial activity, it has been reported for use in <strong>reducing gingival hyperplasia secondary to ciclosporin administration<\/strong> in cases where cessation of treatment is not possible.<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Azithromycin in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<ul>\n<li>5\u201310 mg\/kg p.o. q24h. May increase dosing interval to q48h after 3\u20135 days of treatment.<\/li>\n<\/ul>\n<p><strong>Cats:<\/strong><\/p>\n<p>Various regimes are suggested:<\/p>\n<ul>\n<li>5\u201310 mg\/kg p.o q24h for 3\u20135 days.<\/li>\n<li>5 mg\/kg p.o. q24h for 2 days then every 3\u20135 days up to a total of 5 doses.<\/li>\n<li>For upper respiratory tract disease: 5\u201310 mg\/kg p.o. q24h for 5 days then q72h.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Azithromycin in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>vomiting, cholestatic hepatitis, stomatitis and glossitis may be seen.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Azithromycin in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Avoid in renal and hepatic failure in all species.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Azithromycin activity is enhanced in an alkaline pH; <strong>administer on an empty stomach.<\/strong><\/li>\n<li>Azithromycin may increase the serum levels of methylprednisolone, theophylline and terfenadine. The absorption of digoxin may be enhanced.<\/li>\n<li>It is active against Gram-positive cocci (some Staphylococcus species are resistant), Gram-positive bacilli, some Gram-negative bacilli (Haemophilus, Pasteurella), mycobacteria, obligate anaerobes, Chlamydia, Mycoplasma and Toxoplasma. Some strains of Actinomyces, Nocardia and Rickettsia are also inhibited. <strong>Most strains of the Enterobacteriaceae (Pseudomonas, Escherichia coli, Klebsiella) are resistant.<\/strong><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Azithromycin: Uses, Dosage and Side Effects Overview Time-dependent macrolide that binds to the 50S bacterial ribosome (like erythromycin), inhibiting peptide bond formation. Azithromycin has a longer tissue half-life than erythromycin, shows better oral absorption and is better tolerated in humans. Uses of Azithromycin Alternative to penicillin in allergic individuals as it has a similar, although [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1094,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38],"tags":[],"class_list":["post-306","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-antibacterial"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/306","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=306"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/306\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1094"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=306"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=306"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=306"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}