{"id":294,"date":"2023-02-01T12:45:30","date_gmt":"2023-02-01T10:45:30","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=294"},"modified":"2023-04-21T19:51:29","modified_gmt":"2023-04-21T19:51:29","slug":"atipamezole","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/atipamezole\/","title":{"rendered":"Atipamezole"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Atipamezole: Uses, Dosage and Side Effects<\/strong><\/p>\n<h3><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-420 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/02\/Atipamezole.jpg\" alt=\"Atipamezole: Uses, Dosage and Side Effects\" width=\"661\" height=\"397\" \/><\/h3>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<p>Atipamezole is a selective alpha-2 adrenoreceptor antagonist.<\/p>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Atipamezole<\/strong><\/h2>\n<ul>\n<li>Reverses the sedative effects of medetomidine or dexmedetomidine to provide a quick recovery from anesthesia and sedation.<\/li>\n<li>It also reverses other effects such as the analgesic, cardiovascular and respiratory effects of alpha-2 agonists.<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Atipamezole in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<p>\u2022\u00a0 \u00a0 \u00a0<strong>5 times<\/strong> the previous medetomidine dose or <strong>10 times<\/strong> the previous dose of dexmedetomidine (0.5 mg\/ml solution) i.m. (i.e. equal volume of solution to medetomidine or dexmedetomidine 0.5 mg\/ml solution given). When medetomidine or dexmedetomidine has been administered at least an hour before, the dose of atipamezole can be reduced by half and repeated if recovery is slow.<\/p>\n<p>\u2022 <strong>Amitraz toxicity:<\/strong> 25 \u03bcg (micrograms)\/kg i.m. but if there is no benefit within 30 minutes this can be repeated or incrementally increased every 30 minutes up to 200 \u03bcg\/kg.<\/p>\n<p><strong>Cats:<\/strong><\/p>\n<ul>\n<li><strong>\u00a0 \u00a0 \u00a02.5 times<\/strong> the previous medetomidine or <strong>5 times<\/strong> the previous dose of dexmedetomidine (0.5 mg\/ml solution) i.m. (i.e. half the volume of medetomidine or dexmedetomidine 0.5 mg\/ml solution given). When medetomidine or dexmedetomidine has been administered at least an hour before, the dose of atipamezole can be reduced by half and repeated if recovery is slow.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Atipamezole in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Transient over-alertness and tachycardia may be observed after overdosage.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Atipamezole in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Cannot be recommended during pregnancy.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Atipamezole <strong>should not be<\/strong> administered until at least 30 minutes after medetomidine\/ketamine combinations have been given to cats, to avoid CNS excitation in recovery.<\/li>\n<li>Routine administration of atipamezole i.v. is <strong>not recommended<\/strong> because rapid recovery from sedation is usually associated with excitation, although i.v. administration may be indicated in an emergency (e.g. excessive sedation from medetomidine or dexmedetomidine or cardiovascular complications).<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Atipamezole: Uses, Dosage and Side Effects Overview Atipamezole is a selective alpha-2 adrenoreceptor antagonist. Uses of Atipamezole Reverses the sedative effects of medetomidine or dexmedetomidine to provide a quick recovery from anesthesia and sedation. It also reverses other effects such as the analgesic, cardiovascular and respiratory effects of alpha-2 agonists. Dose of Atipamezole in Dogs [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1080,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[],"class_list":["post-294","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cns"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/294","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=294"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/294\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1080"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=294"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=294"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}