{"id":2933,"date":"2024-07-29T13:43:21","date_gmt":"2024-07-29T10:43:21","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2933"},"modified":"2024-07-27T13:50:20","modified_gmt":"2024-07-27T10:50:20","slug":"trazodone","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/trazodone\/","title":{"rendered":"Trazodone"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Trazodone In Dogs &amp; Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-3091\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2024\/04\/Trazodone.jpg\" alt=\"Trazodone In Dogs &amp; Cats: Uses, Dosage and Side Effects\" width=\"800\" height=\"480\" srcset=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2024\/04\/Trazodone.jpg 800w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2024\/04\/Trazodone-300x180.jpg 300w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2024\/04\/Trazodone-768x461.jpg 768w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2024\/04\/Trazodone-696x418.jpg 696w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2024\/04\/Trazodone-700x420.jpg 700w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>Trazodone is an atypical antidepressant with mixed serotonergic agonistic (5HT1A) and antagonistic actions (other 5HT receptor sites).<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Trazodone<\/strong><\/h2>\n<ul>\n<li>Effective for chronic anxiety in dogs not responding to other medications, but should be combined with behaviour modification.<\/li>\n<li>Caution is needed in dogs with renal disease; monitor carefully.<\/li>\n<li>Lower risk in dogs with cardiac disease compared to tricyclic antidepressants like amitriptyline.<\/li>\n<li>Helpful in reducing anxiety during hospitalization and postoperative confinement in dogs.<\/li>\n<li>Suitable for short-term anxiety management in cats, such as travel or examination anxiety.<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Trazodone in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<ul>\n<li><span style=\"text-decoration: underline;\"><strong>For management of short-term anxiety associated with hospitalization<\/strong><\/span>: 4 mg\/kg p.o. q12h titrated upwards to 10\u201312 mg\/kg as needed to a maximum of 300 mg per dose.<\/li>\n<li><span style=\"text-decoration: underline;\"><strong>For chronic anxiety issues<\/strong><\/span>: initial dose for 5\u201310 kg, 25 mg p.o. q24h; 11\u201320 kg, 50 mg p.o. q24h; &gt;21 kg, 100 mg p.o. q24h.<\/li>\n<li>Doses may be titrated upwards every 10\u201314 days to a maximum of double the recommended initial dose.<\/li>\n<li>Doses for dogs &gt;40 kg may be titrated to a maximum of 300 mg p.o. q24h.<\/li>\n<li>The dose may need to be increased if used long-term as tolerance over time is common.<\/li>\n<li>Lower-end doses may be used adjunctively with SSRIs (e.g. fluoxetine) but not MAOIs, but the risk of serotonin syndrome should be recognized.<\/li>\n<\/ul>\n<p><strong>Cats: <\/strong><\/p>\n<ul>\n<li>50\u2013100 mg\/cat p.o. q24h; for short-term use only; 50 mg\/cat administered 1 hour before travel to address transport and examination-related anxiety.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Trazodone in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Sedation, vomiting, excitability and dry mouth.<\/li>\n<li>Third eyelid protrusion is described in some cats.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Trazodone in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Glaucoma, history of seizures or urinary retention and severe liver disease.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Avoid use with monoamine oxidase inhibitors or drugs metabolized by cytochrome P450 2D6, such as chlorphenamine and cimetidine.<\/li>\n<li>Risk of serotonin syndrome if combined with other serotonergic substances, but adjunctive therapy may be considered in some cases.<\/li>\n<li>Ketoconazole inhibits trazodone breakdown, leading to increased blood levels, while carbamazepine has the opposite effect.<\/li>\n<li>Itraconazole might have a similar effect, though clinical evidence is lacking.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Trazodone In Dogs &amp; Cats: Uses, Dosage and Side Effects Overview Trazodone is an atypical antidepressant with mixed serotonergic agonistic (5HT1A) and antagonistic actions (other 5HT receptor sites). Uses of Trazodone Effective for chronic anxiety in dogs not responding to other medications, but should be combined with behaviour modification. Caution is needed in dogs with [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":3091,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[],"class_list":["post-2933","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-behavior-modifiers"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/2933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=2933"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/2933\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/3091"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=2933"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=2933"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=2933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}