{"id":292,"date":"2023-02-01T12:43:38","date_gmt":"2023-02-01T10:43:38","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=292"},"modified":"2023-04-21T19:49:55","modified_gmt":"2023-04-21T19:49:55","slug":"atenolol","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/atenolol\/","title":{"rendered":"Atenolol"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Atenolol: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-417 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/02\/Atenolol.jpg\" alt=\"Atenolol: Uses, Dosage and Side Effects\" width=\"658\" height=\"395\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>Cardioselective beta-adrenergic blocker.<\/li>\n<li>It is relatively specific for beta-1 adrenergic receptors but can antagonize beta-2 receptors at high doses.<\/li>\n<li>Blocks the chronotropic and inotropic effects of beta-1 adrenergic stimulation on the heart, thereby reducing myocardial oxygen demand.<\/li>\n<li>Bronchoconstrictor, vasodilatory and hypoglycaemic effects are less marked due to its cardioselective nature.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Atenolol <\/strong><\/h2>\n<ul>\n<li>Treatment of <strong>hypertrophic obstructive cardiomyopathy<\/strong> (cats) or <strong>obstructive cardiac disease<\/strong> (severe aortic or pulmonic stenosis).<\/li>\n<li>Treatment of<strong> systemic hypertension<\/strong>.<\/li>\n<li>Can be used following introduction of alpha-blockade in<strong> management of pheochromocytoma.<\/strong><\/li>\n<li>Treatment of <strong>cardiac tachyarrhythmias<\/strong> (including those associated with feline hyperthyroidism).<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Atenolol in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<p>0.2\u20132 mg\/kg p.o. q12h; a lower dose is often used initially with gradual titration upwards if necessary.<\/p>\n<p><strong>Cats:<\/strong><\/p>\n<ul>\n<li><strong>6.25\u201312.5 mg\/cat p.o. q12\u201324h<\/strong>; a lower dose is often used initially with gradual titration upwards if necessary.<\/li>\n<li>If using the oral liquid doses of <strong>0.2\u20132 mg\/kg p.o. q12h can be used<\/strong>, with gradual titration upwards as necessary.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Atenolol in Dogs and Cats<\/strong><\/h2>\n<p>Most frequently seen in geriatric patients with chronic heart disease or in patients with acute or decompensated heart failure.<\/p>\n<p>Include :<\/p>\n<ul>\n<li>bradycardia<\/li>\n<li>AV block<\/li>\n<li>Myocardial depression<\/li>\n<li>Heart failure<\/li>\n<li>Syncope<\/li>\n<li>Hypotension<\/li>\n<li>Hypoglycaemia<\/li>\n<li>Bronchospasm<\/li>\n<li>Diarrhea.<\/li>\n<li>Depression and lethargy may occur as a result of atenolol\u2019s high lipid solubility and its penetration into the CNS<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Atenolol in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Patients with bradyarrhythmias<\/li>\n<li>Patients with acute or decompensated congestive heart failure.<\/li>\n<li>Relatively contraindicated in animals with medically controlled congestive heart failure as it is poorly tolerated.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Do not administer concurrently with alpha-adrenergic agonists (e.g. phenylpropanolamine) unless specific indication (phaeochromocytoma).<\/li>\n<li>The <strong>hypotensive effect of atenolol is enhanced<\/strong> by many agents that depress myocardial activity including anesthetic agents, phenothiazines, antihypertensive drugs, diuretics and diazepam. There is an increased risk of bradycardia, severe hypotension, heart failure and AV block if atenolol is used concurrently with <strong>calcium-channel blockers.<\/strong><\/li>\n<li>Concurrent <strong>digoxin<\/strong> administration potentiates bradycardia.<\/li>\n<li>The<strong> metabolism<\/strong> of atenolol is accelerated by thyroid hormones; thus, the dose of atenolol may need to be decreased when initiating carbimazole therapy. Atenolol enhances the effects of muscle relaxants (e.g. suxamethonium, tubocurarine).<\/li>\n<li>Hepatic enzyme induction by <strong>phenobarbital<\/strong> may increase the rate of metabolism of atenolol.<\/li>\n<li>The bronchodilatory effects of<strong> theophylline<\/strong> may be blocked by atenolol. Atenolol may enhance the hypoglycaemic effect of insulin<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Atenolol: Uses, Dosage and Side Effects Overview Cardioselective beta-adrenergic blocker. It is relatively specific for beta-1 adrenergic receptors but can antagonize beta-2 receptors at high doses. Blocks the chronotropic and inotropic effects of beta-1 adrenergic stimulation on the heart, thereby reducing myocardial oxygen demand. Bronchoconstrictor, vasodilatory and hypoglycaemic effects are less marked due to its [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1077,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[49],"class_list":["post-292","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cardiovascular","tag-beta-adrenergic-blocker"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=292"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/292\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1077"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=292"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=292"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}