{"id":2917,"date":"2024-05-12T23:30:53","date_gmt":"2024-05-12T20:30:53","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2917"},"modified":"2024-05-12T23:30:53","modified_gmt":"2024-05-12T20:30:53","slug":"ursodeoxycholic-acid-udca","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/ursodeoxycholic-acid-udca\/","title":{"rendered":"Ursodeoxycholic Acid (UDCA)"},"content":{"rendered":"

Ursodeoxycholic acid (UDCA) In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Ursodeoxycholic$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Ursodeoxycholic acid is a hydrophilic bile acid known for its cytoprotective effects in the biliary system.<\/li>\n
It works by inhibiting the ileal absorption of hydrophobic bile acids, thereby decreasing their concentration in the body pool.<\/li>\n
Hydrophobic bile acids can be toxic to hepatobiliary cell membranes and may worsen cholestasis.<\/li>\n
Ursodeoxycholic acid also possesses immunomodulatory properties and may influence the apoptosis of hepatocytes.<\/li>\n<\/ul>\n
Uses of Ursodeoxycholic acid (UDCA)<\/strong><\/h2>\n
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Ursodeoxycholic acid (UDCA) serves as adjunctive therapy for patients with liver disease, especially those with cholestasis.<\/li>\n
In normal healthy dogs, the administration of UDCA does not affect the bile acid stimulation test.<\/li>\n
However, in healthy cats, both pre-and postprandial bile acids show a slight but significant increase after UDCA administration.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Ursodeoxycholic acid (UDCA) in Dogs and Cats<\/strong><\/h2>\n
Dogs, Cats: <\/strong><\/p>\n
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10\u201315 mg\/kg p.o. q24h or divided daily.<\/li>\n<\/ul>\n
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