{"id":288,"date":"2023-02-01T12:39:27","date_gmt":"2023-02-01T10:39:27","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=288"},"modified":"2023-04-21T19:45:23","modified_gmt":"2023-04-21T19:45:23","slug":"aspirin-acetylsalicyclic-acid","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/aspirin-acetylsalicyclic-acid\/","title":{"rendered":"Aspirin (Acetylsalicyclic acid)"},"content":{"rendered":"

Aspirin (Acetylsalicylic acid) : Uses, Dosage, and Side Effects<\/strong><\/p>\n

$\"Aspirin$ <\/h3>\n\n
Overview<\/strong><\/h2>\n
Acetylsalicylic acid produces irreversible inhibition of cyclo-oxygenase (COX-1, prostaglandin synthetase) by acetylation, thereby preventing the production of both prostaglandins and thromboxanes from membrane phospholipids.<\/p>\n
Uses of Aspirin (Acetylsalicylic acid) <\/strong><\/h2>\n
\n
Prevention of arterial thromboembolism.<\/li>\n
Also can be used to control mild to moderate pain, although NSAIDs that are more selective for the COX-2 enzyme have a better safety profile; not an NSAID of choice for analgesia in dogs or cats.<\/strong><\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Aspirin (Acetylsalicylic acid) in Dogs and Cats<\/strong><\/h2>\n
Dogs: (<\/strong>\u00a0Doses are anecdotal and the ideal doses are unknown.)<\/strong><\/em><\/p>\n
\n
Reduction of platelet aggregation (e.g. IMHA)<\/strong>: 0.5\u20131 mg\/kg p.o. q24h or 0.5 mg\/kg p.o. q12h.<\/li>\n
Analgesia, pyrexia, inflammation<\/strong>: doses range from 10 mg\/kg to 20 mg\/kg p.o. q12h.<\/li>\n<\/ul>\n
Cats:<\/strong><\/p>\n
\n
Reduction of platelet aggregation<\/strong>:<\/li>\n
\u00bc of a 75 mg tablet (18.75 mg) p.o for an average-sized cat 3 days a week (low dose) or, alternatively, 75 mg for an average-sized cat 3 days a week (high dose); this dose may be associated with a higher risk of GI side effects.<\/li>\n
Some authors suggest a very low dose (0.5 mg\/kg p.o. q24h) to inhibit platelet COX without preventing the beneficial effects of prostacyclin production.<\/li>\n<\/ul>\n
\n \n \n